Shibli Jamil A, Pires Jefferson T, Piattelli Adriano, Iezzi Giovanna, Mangano Carlo, Mangano Francesco, de Souza Sergio L S, Gehrke Sergio A, Wang Hom-Lay, Ehrenfest David M Dohan
Department of Periodontology and Oral Implantology, Guarulhos University, Sao Paulo, Praca Teresa Cristina, 229 Centro - Guarulhos - SP, - CEP 07023-070, Brazil.
Department of Periodontics and Oral Medicine, The University of Michigan, School of Dentistry, Ann Arbor, Michigan, United States.
Curr Pharm Biotechnol. 2017;18(1):76-84. doi: 10.2174/1389201017666161221120618.
The high success range obtained with the implant-supported restorations has improved its applicability on routine of the daily clinical practice. This elevated percentage of success is related to the previous pre-clinical data obtained from animal and in vitro studies that evaluated the impact of implant surface topographies on bone tissue. However, the histological evaluation of human bone tissue is scarce. Therefore, the aim of this review is to depict an actual panorama of the data available on boneto- implant contact (BIC) of retrieved implants from human jaws. Some aspects of implant surface topography as well as systemic conditions as osteoporosis and smoking habit were demonstrated to have a strong impact, suggesting that the data obtained from human bone tissue is still valuable for the better understanding of the osseointegration process. This article also highlighted that most data in humans are difficult to interpret, due to the lack of detailed information about the surfaces found in retrieved implants. Without the definition of the surface characteristics, it is difficult to link exactly the surface patterns to specific clinical observations, and all observations remain de facto incomplete. As a conclusion, data from implants retrieved from human jaws are very important for our understanding, however the studies remain scarce and data is fragmented. This important approach should be improved, completed and developed in the future.
种植体支持修复体所取得的高成功率提高了其在日常临床实践中的适用性。这种较高的成功率与先前从动物和体外研究中获得的临床前数据有关,这些研究评估了种植体表面形貌对骨组织的影响。然而,对人类骨组织的组织学评估却很少。因此,本综述的目的是描绘从人类颌骨中取出的种植体的骨结合(BIC)方面现有数据的实际情况。种植体表面形貌的一些方面以及诸如骨质疏松症和吸烟习惯等全身状况已被证明有很大影响,这表明从人类骨组织获得的数据对于更好地理解骨整合过程仍然很有价值。本文还强调,由于缺乏关于取出的种植体表面的详细信息,大多数人类数据难以解释。如果没有表面特征的定义,就很难将表面模式与特定的临床观察结果准确联系起来,而且所有观察结果实际上都不完整。总之,从人类颌骨中取出的种植体的数据对于我们的理解非常重要,然而相关研究仍然很少,数据也很零散。这种重要的方法在未来应该得到改进、完善和发展。