Raes Filiep, Eccellente Tammaro, Lenzi Carolina, Ortolani Michele, Luongo Giuseppe, Mangano Carlo, Mangano Francesco
Professor, Department of Periodontology and Oral Implantology, University of Ghent, Belgium.
Private Practice, Grumo Nevano, Naples, Italy.
J Dent Res Dent Clin Dent Prospects. 2018 Winter;12(1):26-37. doi: 10.15171/joddd.2018.005. Epub 2018 Mar 14.
In the current scientific literature there are only few studies on the immediate functional loading of single implants. The aim of the present present study was to evaluate the 4-year survival rate, complication rate and peri-implant marginal bone loss (PIMBL) of immediately loaded single implants inserted in healed ridges and fresh post-extraction sites. Six centers were involved in this prospective study. The surgical and prosthetic protocol was defined in detail, before the start of recruiting patients. Recruitment of patients and performance of surgeries took place between February 2012 and February 2013. Criteria for inclusion were single-tooth gaps in healed ridges and fresh post-extraction sockets. All the fixtures (Anyridge®, Megagen Corporation, Gyeongbuk, South Korea) were functionally loaded immediately after insertion and followed for a period of 4 years. Outcome measures were implant survival, complications and PIMBL. Forty-six patients (18‒73 years of age) were selected. In total, 57 fixtures were placed (10 in fresh post-extraction sockets). After 4 years of functional loading, only one fixture was lost; therefore, high survival rates (97.6% patient-based; 98.1% implant-based) were reported. In addition, a limited incidence of biologic (4.8% patient-based; 3.8% implant-based) and prosthetic (9.7% patient-based; 7.6% implant-based) complications was reported. The overall 4-year PIMBL amounted to 0.38±0.21 mm (healed ridges: 0.4±0.21 mm; fresh post-extraction sockets: 0.33±0.20 mm). Loading single implants immediately seems to be a highly successful treatment modality. However, long-term data are needed to confirm these positive outcomes.
在当前的科学文献中，关于单个种植体即刻功能负载的研究很少。本研究的目的是评估植入愈合牙槽嵴和新鲜拔牙位点的即刻负载单个种植体的4年生存率、并发症发生率和种植体周围边缘骨吸收（PIMBL）情况。六个中心参与了这项前瞻性研究。在开始招募患者之前，详细定义了手术和修复方案。患者招募和手术于2012年2月至2013年2月期间进行。纳入标准为愈合牙槽嵴和新鲜拔牙窝中的单牙间隙。所有种植体（Anyridge®，韩国庆尚北道Megagen公司）在植入后即刻进行功能负载，并随访4年。观察指标为种植体生存率、并发症和PIMBL。选择了46例患者（年龄18 - 73岁）。总共植入了57颗种植体（10颗植入新鲜拔牙窝）。经过4年的功能负载，仅一颗种植体丢失；因此，报告了较高的生存率（基于患者为97.6%；基于种植体为98.1%）。此外，报告的生物学并发症（基于患者为4.8%；基于种植体为3.8%）和修复并发症（基于患者为9.7%；基于种植体为7.6%）发生率有限。4年总的PIMBL为0.38±0.21 mm（愈合牙槽嵴：0.4±0.21 mm；新鲜拔牙窝：0.33±0.20 mm）。即刻负载单个种植体似乎是一种非常成功的治疗方式。然而，需要长期数据来证实这些积极结果。
