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使用颈椎椎弓根螺钉进行后路颈椎融合术后1年,通过计算机断层扫描测量融合和植骨吸收速率的分析

Analysis of the Fusion and Graft Resorption Rates, as Measured by Computed Tomography, 1 Year After Posterior Cervical Fusion Using a Cervical Pedicle Screw.

作者信息

Lee Jae Koo, Jung Sang Ku, Lee Young-Seok, Jeon Sang Ryong, Roh Sung Woo, Rhim Seung Chul, Park Jin Hoon

机构信息

Department of Neurological Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Department of Emergency Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine, Gangneung, Korea.

出版信息

World Neurosurg. 2017 Mar;99:171-178. doi: 10.1016/j.wneu.2016.12.027. Epub 2016 Dec 19.

Abstract

BACKGROUND

We previously showed that cervical pedicle screw (CPS) placement is safe even with the freehand technique. The posterolateral fusion rate 1 year after CPS placement, as measured by computed tomography (CT), is reported here. The graft resorption rates when different graft materials were used were also analyzed.

METHODS

Between 2012 and 2015, 93 patients underwent posterior cervical fusion surgery with the CPS from C2 to C7. Of these patients, 56 consented to CT scans immediately and 1 year after surgery. These patients formed the present study group. The patients were categorized according to whether the graft material was local bone, allograft, or a mixture. Graft volume was measured at both CT scans. Graft resorption rate was determined by comparing the 2 scans. Radiologic fusion was assessed on the 1 year postoperative CT scan and radiography.

RESULTS

The reason for surgery was trauma (n = 19), degenerative disease (n = 35), tumor (n = 1), and spondylitis (n = 1). Surgery was performed with CPS fixation and decompression. Even although iliac bone grafting was not performed, the overall fusion rate was 98.2% (55/56). The single fusion failure case received a mixture of local bone and allograft. Although the allograft group showed the greatest graft resorption rate (91.5%), all patients in this group had a bony bridge that crossed the facet joint on the 1 year CT scan.

CONCLUSIONS

CPS placement yielded a posterolateral cervical fusion rate of 98.2%. Despite the high resorption rate of allograft only, this material yielded fusion rates that were similar to those of the other materials. Thus, the strong fixation power of CPS might compensate for the delayed fusion and high resorption rates of allograft bone chips.

摘要

背景

我们之前表明,即使采用徒手技术,颈椎椎弓根螺钉(CPS)置入也是安全的。本文报告了通过计算机断层扫描(CT)测量的CPS置入术后1年的后外侧融合率。还分析了使用不同移植材料时的植骨吸收率。

方法

2012年至2015年期间,93例患者接受了C2至C7节段的CPS后路颈椎融合手术。其中,56例患者同意在术后即刻和1年时进行CT扫描。这些患者构成了本研究组。根据移植材料是自体骨、同种异体骨还是混合骨,将患者进行分类。在两次CT扫描时均测量植骨体积。通过比较两次扫描结果确定植骨吸收率。在术后1年的CT扫描和X线片上评估影像学融合情况。

结果

手术原因包括创伤(n = 19)、退行性疾病(n = 35)、肿瘤(n = 1)和脊柱炎(n = 1)。手术采用CPS固定和减压。即使未进行髂骨植骨,总体融合率仍为98.2%(55/56)。唯一融合失败的病例接受了自体骨和同种异体骨的混合移植。尽管同种异体骨组的植骨吸收率最高(91.5%),但该组所有患者在术后1年的CT扫描上均有跨越小关节的骨桥形成。

结论

CPS置入后的颈椎后外侧融合率为98.2%。尽管仅同种异体骨的吸收率较高,但该材料产生的融合率与其他材料相似。因此,CPS强大的固定能力可能弥补了同种异体骨碎块延迟融合和高吸收率的问题。

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