Tuck Matthew, Lim Jane, Lucar Jose, Benator Debra
Department of Medicine, George Washington University, Washington, DC, USA.
Department of Medical Services (111), Veterans Affairs Medical Center, Washington, DC, USA.
BMJ Case Rep. 2016 Dec 21;2016:bcr2016217317. doi: 10.1136/bcr-2016-217317.
The presentation of anaplastic lymphoma kinase protein (ALK)-negative anaplastic large cell lymphoma (ALCL) in bone is rare. We describe a patient with ALK-negative ALCL presenting with clinical and radiographic findings suggesting osteomyelitis 6 months after left rotator cuff repair surgery. A review of the characteristics of ALK-negative ALCL with primary bone involvement is presented. ALCL should be considered in patients not responding to therapies for osteomyelitis.
间变性淋巴瘤激酶蛋白（ALK）阴性的间变性大细胞淋巴瘤（ALCL）累及骨骼的情况罕见。我们描述了1例ALK阴性的ALCL患者，该患者在左旋转袖套修复手术后6个月出现提示骨髓炎的临床和影像学表现。本文对原发性骨受累的ALK阴性ALCL的特征进行了综述。对于骨髓炎治疗无反应的患者应考虑ALCL。
