Beutler Bryce David, Krishan Rohee, Parafianowicz Pawel, Ulanja Mark B, Elliott Christie, France Joel, Islam Raheel, Gullapalli Nageshwara
Department of Internal Medicine Reno School of Medicine University of Nevada Reno NV USA.
Department of Pathology and Laboratory Medicine Reno School of Medicine University of Nevada Reno NV USA.
Clin Case Rep. 2020 Jan 20;8(2):327-332. doi: 10.1002/ccr3.2630. eCollection 2020 Feb.
Diffuse large B-cell lymphoma often presents with extranodal manifestations involving the musculoskeletal system. Shoulder pain is particularly worrisome for malignancy. Individuals presenting with refractory upper extremity complaints should undergo a prompt and thorough evaluation for cancer, as a delay in diagnosis can result in an unfavorable outcome.
弥漫性大B细胞淋巴瘤常表现为累及肌肉骨骼系统的结外表现。肩部疼痛对于恶性肿瘤而言尤其令人担忧。出现难治性上肢症状的患者应迅速接受全面的癌症评估,因为诊断延迟可能导致不良后果。