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青少年拔毛治疗的习惯逆转训练初步随机对照试验。

Preliminary Randomized Controlled Trial of Habit Reversal Training for Treatment of Hair Pulling in Youth.

作者信息

Rahman Omar, McGuire Joseph, Storch Eric A, Lewin Adam B

机构信息

1 Department of Pediatrics, University of South Florida , Tampa, Florida.

2 Department of Psychiatry and Behavioral Neurosciences, University of South Florida , Tampa, Florida.

出版信息

J Child Adolesc Psychopharmacol. 2017 Mar;27(2):132-139. doi: 10.1089/cap.2016.0085. Epub 2016 Dec 22.

Abstract

OBJECTIVES

This study evaluated the treatment efficacy of habit reversal training (HRT) relative to treatment as usual (TAU) for children and adolescents aged 7-17 years with a primary diagnosis of trichotillomania (TTM).

METHOD

An initial assessment consisting of semistructured interviews and rating scales was conducted. Participants (N = 40, 85% female) meeting diagnostic criteria for TTM were randomized to either 8 weekly sessions of HRT by trained therapists or 8 weeks of TAU. One week after the final HRT session or final TAU week, patients completed a posttreatment assessment, followed by 1- and 3-month follow-up assessments. All assessments were conducted by a trained rater who was blinded to treatment condition.

RESULTS

The group by time analysis of variance yielded a significant interaction on the National Institute of Mental Health-Trichotillomania Severity Scale Total Score (F = 16.47, p < 0.001, η = 0.30). The mean score decreased from 12.67 ± 4.60 at baseline to 5.62 ± 4.38 at posttreatment in the HRT group (t = 5.99, p < 0.001, d = 1.31), whereas the TAU group changed from 10.42 ± 4.35 to 9.32 ± 4.11 (t = 1.34, p = 0.20, d = 0.31). The Massachusetts General Hospital-Hair Pulling Scale Total Score decreased from 15.14 ± 3.86 at baseline to 7.14 ± 5.54 at posttreatment in the HRT group (t = 6.16, p < 0.001, d = 1.34); the TAU group changed from 14.16 ± 4.51 to 12.26 ± 4.34 (t = 1.50, p = 0.15, d = 0.34). On the Clinical Global Impressions-Improvement, 16/21 participants (76%) were rated as treatment responders in the HRT group versus 4/19 (21%) in the TAU group (χ = 12.13, p < 0.001, V = 0.55). At 1-month follow-up, 10-12 treatment responders who completed the assessment maintained improvement. At 3-month follow-up, six of eight maintained improvement.

CONCLUSIONS

HRT can be an effective treatment for TTM in youth.

摘要

目的

本研究评估了习惯逆转训练(HRT)相对于常规治疗(TAU)对7至17岁原发性拔毛癖(TTM)儿童和青少年的治疗效果。

方法

进行了包括半结构化访谈和评定量表的初始评估。符合TTM诊断标准的参与者(N = 40,85%为女性)被随机分为由训练有素的治疗师进行的8次每周HRT治疗或8周的TAU治疗。在最后一次HRT治疗或最后一次TAU治疗周后的一周,患者完成治疗后评估,随后进行1个月和3个月的随访评估。所有评估均由对治疗条件不知情的训练有素的评估者进行。

结果

组间时间方差分析在国立精神卫生研究所拔毛癖严重程度量表总分上产生了显著交互作用(F = 16.47,p < 0.001,η = 0.30)。HRT组的平均得分从基线时的12.67±4.60降至治疗后的5.62±4.38(t = 5.99,p < 0.001,d = 1.31),而TAU组从10.42±4.35变为9.32±4.11(t = 1.34,p = 0.20,d = 0.31)。HRT组的马萨诸塞州总医院拔毛量表总分从基线时的15.14±3.86降至治疗后的7.14±5.54(t = 6.16,p < 0.001,d = 1.34);TAU组从14.16±4.51变为12.26±4.34(t = 1.50,p = 0.15,d = 0.34)。在临床总体印象改善方面,HRT组21名参与者中有16名(76%)被评为治疗有反应者,而TAU组19名中有4名(21%)(χ = 12.13,p < 0.001,V = 0.55)。在1个月随访时,完成评估的10 - 12名治疗有反应者维持了改善。在3个月随访时,8名中有6名维持了改善。

结论

HRT可以是治疗青少年TTM的有效方法。

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