Lee Melissa T, Mpavaenda Davis N, Fineberg Naomi A
Hertfordshire Partnership University NHS Foundation Trust, Welwyn Garden City, United Kingdom.
University of Hertfordshire, Hatfield, United Kingdom.
Front Behav Neurosci. 2019 Apr 24;13:79. doi: 10.3389/fnbeh.2019.00079. eCollection 2019.
Habit Reversal Therapy (HRT) has long been used in the treatment of Tourette Syndrome and Tic Disorders. It has more recently been used to treat Trichotillomania and skin picking behaviors, both considered as Obsessive Compulsive Related Disorders (OCRD). This literature review sought to establish and quality assess the existing randomized controlled trial evidence supporting the use of HRT in the DSM-5 family of OCRDs. EMBASE, PsycINFO, PubMed, and Cochrane databases were searched for key terms relating to each OCRD (as classified in the DSM-5), and HRT. Titles and abstracts were screened, and any literature matching pre-specified criteria were then selected to be reviewed further. Of these, 8 Randomized Controlled Trials (RCT) relating to Trichotillomania, and 2 RCTs relating to Excoriation Disorder, were extracted and reviewed against the 2010 Consolidating Standards of Reporting Trials (CONSORT) statement. The review identified 10 RCTs of HRT, but these were limited to patients with a primary diagnosis of Trichotillomania or "excoriation behavior," only. There were some reports of the use of HRT in Tourette Syndrome or Tic Disorder with secondary OCD, but the OCD symptoms were not reliably reported on. There is a gap in the current literature regarding the use of HRT in the DSM-5 OCRDs. In those RCTs that have been reported, the quality of study methodology was questionable as evaluated by CONSORT criteria. The implications of these findings are discussed, and suggestions are made for future research.
习惯逆转疗法(HRT)长期以来一直用于治疗抽动秽语综合征和抽动障碍。最近,它也被用于治疗拔毛癖和皮肤搔抓行为,这两种行为都被视为强迫症相关障碍(OCRD)。这篇文献综述旨在确立并评估现有的随机对照试验证据,以支持在DSM-5的OCRD类别中使用HRT。在EMBASE、PsycINFO、PubMed和Cochrane数据库中搜索与每种OCRD(如DSM-5中分类)以及HRT相关的关键词。对标题和摘要进行筛选,然后选择任何符合预先指定标准的文献进行进一步审查。其中,提取了8项与拔毛癖相关的随机对照试验(RCT)以及2项与皮肤搔抓障碍相关的RCT,并根据2010年《报告试验的统一标准》(CONSORT)声明进行审查。该综述确定了10项HRT的RCT,但这些试验仅限于原发性诊断为拔毛癖或“皮肤搔抓行为”的患者。有一些关于在抽动秽语综合征或伴有继发性强迫症的抽动障碍中使用HRT的报告,但强迫症症状并未得到可靠报告。目前关于在DSM-5的OCRD中使用HRT的文献存在空白。在已报告的那些RCT中,根据CONSORT标准评估,研究方法的质量存在问题。讨论了这些发现的意义,并对未来研究提出了建议。