Contreras-Haro Betsabe, Robles-Cervantes Jose A, Gonzalez-Ortiz Manuel, Martinez-Abundis Esperanza, Espinel-Bermudez Claudia, Gallegos-Arreola Martha P, Morgado-Castillo Karina C
1 Medical Research Unit in Clinical Epidemiology, Specialties Hospital, Medical Unit of High Speciality, West National Medical Center, Mexican Institute of Social Security , Guadalajara. México.
2 Institute of Experimental and Clinical Therapeutics, University of Guadalajara , Guadalajara, México.
J Med Food. 2017 Feb;20(2):197-199. doi: 10.1089/jmf.2016.0116. Epub 2016 Dec 22.
This study was performed to investigate the effect of Agave tequilana Weber inulin on postprandial ghrelin levels in obese patients. A randomized, double-blind, cross-over design was performed. A total of 14 patients were allocated into two groups: one group received a drink that contained 500 mL lemon water, 24 g of A. tequilana Weber inulin, and 75 g glucose and the other group received a placebo drink with 500 mL lemon drink and 75 g of glucose. After a 7-day washout period, the groups were crossed. The primary outcome measure was postprandial ghrelin levels between minute 240 and minute 270. A. tequilana Weber inulin did not change postprandial ghrelin concentration in obese patients.
本研究旨在探讨龙舌兰韦伯菊粉对肥胖患者餐后胃饥饿素水平的影响。采用随机、双盲、交叉设计。总共14名患者被分为两组:一组饮用含有500毫升柠檬水、24克龙舌兰韦伯菊粉和75克葡萄糖的饮料,另一组饮用含有500毫升柠檬饮料和75克葡萄糖的安慰剂饮料。经过7天的洗脱期后,两组进行交叉。主要观察指标是第240分钟至第270分钟之间的餐后胃饥饿素水平。龙舌兰韦伯菊粉并未改变肥胖患者的餐后胃饥饿素浓度。