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男性乳腺癌:改良根治性乳房切除术还是保乳手术?一例病例报告及文献综述。

Male breast cancer: Modified radical mastectomy or breast conservation surgery? A case report and review of the literature.

作者信息

Giunta Gabriele, Rossi Matteo, Toia Francesca, Rinaldi Gaetana, Cordova Adriana

机构信息

Plastic and Reconstructive Surgery, Department of Surgical, Oncological and Oral Sciences, University of Palermo, Via del Vespro, 129, 90127 Palermo, Italy.

Plastic and Reconstructive Surgery, Department of Surgical, Oncological and Oral Sciences, University of Palermo, Via del Vespro, 129, 90127 Palermo, Italy.

出版信息

Int J Surg Case Rep. 2017;30:89-92. doi: 10.1016/j.ijscr.2016.11.030. Epub 2016 Nov 19.

Abstract

INTRODUCTION

Male breast cancer (MBC) is a rare disease that accounts for <1% of breast cancer cases. The most common treatment is modified radical mastectomy (MRM). Recently, breast conservative surgery (BCS) is getting popular for MBC treatment. We report a case and reviewed the literature to investigate whether emerging BCS can be considered as an alternative of a more radical surgery.

PRESENTATION OF CASE

A 46 y.o. patient, presented with a painless left breast lump over a period of six months. The patient underwent a quadrantectomy at another institution. Pathology revealed an intraductal carcinoma in close proximity to the margins of excision. Adjuvant hormonal therapy was proposed to the patient, who refused and was referred to our Institution. We performed a MRM and a sentinel lymph node biopsy (SLNB). A contralateral breast liposuction and an adenectomy were also performed. The patient underwent also a nipple-areolar complex reconstruction. The patient didn't receive adjuvant therapy.

DISCUSSION

Both oncological safety and satisfactory cosmetic outcomes are the goals of MBC treatment. No specific guidelines for MBC treatment have been proposed. MRM is currently the surgical gold standard of MBC (approximately 70% of all cases). Some authors reported that male BCS associated with radiation therapy is a feasible alternative MRM. Taking into account data from the literature and considering the previous surgery, in the case we report, we offered a MRM, SLNB and a contralateral breast symmetrization.

CONCLUSION

MRM with SLNB and reconstruction of male breast asymmetry should be still considered as the treatment of choice of MBC.

摘要

引言

男性乳腺癌(MBC)是一种罕见疾病,占乳腺癌病例的比例不到1%。最常见的治疗方法是改良根治性乳房切除术(MRM)。近来,保乳手术(BCS)在MBC治疗中越来越受欢迎。我们报告了一例病例并回顾文献,以研究新兴的BCS是否可被视为更激进手术的替代方案。

病例介绍

一名46岁患者,六个月来左侧乳房有无痛性肿块。该患者在另一机构接受了象限切除术。病理显示导管内癌,切缘接近。向患者提议辅助激素治疗,患者拒绝并转诊至我院。我们进行了MRM和前哨淋巴结活检(SLNB)。还进行了对侧乳房抽脂术和腺切除术。患者还接受了乳头乳晕复合体重建。患者未接受辅助治疗。

讨论

肿瘤学安全性和令人满意的美容效果都是MBC治疗的目标。尚未提出MBC治疗的具体指南。MRM目前是MBC的手术金标准(约占所有病例的70%)。一些作者报告说,男性BCS联合放疗是MRM的一种可行替代方案。考虑到文献数据并结合之前的手术情况,在我们报告的病例中,我们提供了MRM、SLNB和对侧乳房对称化手术。

结论

MRM联合SLNB及男性乳房不对称重建仍应被视为MBC的首选治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de17/5192241/b6abcad93c1f/gr1.jpg

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