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男性三阴性乳腺癌

Male Triple-Negative Breast Cancer.

作者信息

Qavi Qasif, Alkistawi Firas, Kumar Shashi, Ahmed Rizwan, Saad Abdalla Al-Zawi Abdalla

机构信息

Surgery, Basildon and Thurrock University Hospital, Basildon, GBR.

Surgery, Mid and South Essex NHS Foundation Trust, Basildon, GBR.

出版信息

Cureus. 2021 Apr 18;13(4):e14542. doi: 10.7759/cureus.14542.

Abstract

Male breast cancer is a rarely encountered disease, when compared with female breast cancer, often detected in more advanced stage at the time of diagnosis, and associated with more lymph node metastasis rates, more estrogen receptors positivity, and less human epidermal growth factor receptor-2 expression (HER-2) rates. Surgical management also shows some difference, where the most common operative technique of male breast cancer patients is mastectomy and/or axillary surgery. Triple-negative breast cancer is less frequent than other subtypes and is associated with poorer prognosis. This is because of its association with higher histopathological grade than that in other types of breast cancer. Only fewer treatment options are available compared to hormone-positive, HER-2 positive breast cancer. We are present a case of 71-year-old gentleman with triple-negative breast cancer.

摘要

男性乳腺癌是一种罕见疾病,与女性乳腺癌相比,其在诊断时往往处于更晚期,且伴有更高的淋巴结转移率、更多的雌激素受体阳性率以及更低的人表皮生长因子受体2(HER-2)表达率。手术治疗也存在一些差异,男性乳腺癌患者最常见的手术方式是乳房切除术和/或腋窝手术。三阴性乳腺癌比其他亚型少见,且预后较差。这是因为其组织病理学分级高于其他类型的乳腺癌。与激素阳性、HER-2阳性乳腺癌相比,三阴性乳腺癌的治疗选择较少。我们现报道一例71岁患三阴性乳腺癌的男性患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84fd/8130197/e1ed7ba98a04/cureus-0013-00000014542-i01.jpg

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