Miyata Kazunori, Ogata Miyuki, Honbo Masato, Mori Yosai, Minami Keiichiro
From the Miyata Eye Hospital, Miyakonojo, Japan.
From the Miyata Eye Hospital, Miyakonojo, Japan.
J Cataract Refract Surg. 2016 Dec;42(12):1716-1720. doi: 10.1016/j.jcrs.2016.09.019.
To clinically examine the suppression of surface light scattering after implantation of an intraocular lens (IOL) manufactured using an improved production process.
Miyata Eye Hospital, Miyazaki, Japan.
Comparative case series.
The prospective case series comprised eyes receiving hydrophobic acrylic Acrysof SN60WF IOLs that were manufactured before and after the improvement. Light scattering on the anterior IOL surface was examined up to 3 years postoperatively using an EAS-1000 anterior segment analyzer. The changes during the postoperative period were evaluated and the 2 IOLs compared. The corrected distance visual acuity (CDVA) and contrast sensitivity under photopic and mesopic conditions were also examined 3 years postoperatively.
The case series comprised 24 eyes (received IOL before improvement) and 27 eyes (received IOL after improvement). After the improvement, the IOLs showed no increase in surface light scattering up to 2 years, while there were increases after 2 years in the other IOLs. The light scattering with the improved IOL was significantly reduced at all observations (P < .048, t test with Holm correction). No difference was found in the CDVA and contrast sensitivity.
The improvement in the production process effectively decreased and slowed the development of surface light scattering. The slower increase in the improved IOL 3 years postoperatively showed that the development of water aggregates would not be completely prevented.
None of the authors has a financial or proprietary interest in any material or method mentioned.
临床研究使用改进生产工艺制造的人工晶状体（IOL）植入后表面光散射的抑制情况。
日本宫崎县宫田眼科医院。
比较病例系列。
前瞻性病例系列包括接受改进前后制造的疏水丙烯酸酯Acrysof SN60WF IOL的眼睛。使用EAS - 1000眼前节分析仪在术后长达3年的时间内检查IOL前表面的光散射情况。评估术后期间的变化并比较这两种IOL。术后3年还检查了矫正远视力（CDVA）以及明视和微光条件下的对比敏感度。
病例系列包括24只眼（接受改进前的IOL）和27只眼（接受改进后的IOL）。改进后，IOL在2年内表面光散射没有增加，而其他IOL在2年后出现增加。在所有观察点，改进后的IOL的光散射均显著降低（P <.048，经霍尔姆校正的t检验）。CDVA和对比敏感度未发现差异。
生产工艺的改进有效降低并减缓了表面光散射的发展。改进后的IOL术后3年光散射增加较慢表明水聚集体的形成无法完全预防。
作者均未对文中提及的任何材料或方法拥有财务或专利权益。
