Yuan J, Usman A, Das T, Patterson A J, Gillard J H, Graves M J
From the Department of Radiology (J.Y., A.U., J.H.G., M.J.G.), University of Cambridge, Cambridge, UK
From the Department of Radiology (J.Y., A.U., J.H.G., M.J.G.), University of Cambridge, Cambridge, UK.
AJNR Am J Neuroradiol. 2017 Apr;38(4):664-671. doi: 10.3174/ajnr.A5026. Epub 2016 Dec 22.
Atherosclerosis remains the leading cause of long-term mortality and morbidity worldwide, despite remarkable advancement in its management. Vulnerable atherosclerotic plaques are principally responsible for thromboembolic events in various arterial territories such as carotid, coronary, and lower limb vessels. Carotid plaque ulceration is one of the key features associated with plaque vulnerability and is considered a notable indicator of previous plaque rupture and possible future cerebrovascular events. Multiple imaging modalities have been used to assess the degree of carotid plaque ulceration for diagnostic and research purposes. Early diagnosis and management of carotid artery disease could prevent further cerebrovascular events. In this review, we highlight the merits and limitations of various imaging techniques for identifying plaque ulceration.
尽管在动脉粥样硬化的管理方面取得了显著进展，但它仍然是全球长期死亡率和发病率的主要原因。易损性动脉粥样硬化斑块是导致颈动脉、冠状动脉和下肢血管等不同动脉区域血栓栓塞事件的主要原因。颈动脉斑块溃疡是与斑块易损性相关的关键特征之一，被认为是既往斑块破裂和未来可能发生脑血管事件的重要指标。为了诊断和研究目的，多种成像方式已被用于评估颈动脉斑块溃疡的程度。颈动脉疾病的早期诊断和管理可以预防进一步的脑血管事件。在本综述中，我们强调了各种成像技术在识别斑块溃疡方面的优点和局限性。
