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[酒精性母亲后代胚胎脑细胞的超微结构特征]

[Ultrastructural characteristics of embryonic brain cells in the offspring of alcoholic mothers].

作者信息

Solonskiĭ A V, Kovetskiĭ N S

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1989;89(7):41-5.

PMID:2800810
Abstract

Electron microscopy of brain cells was performed in 20 human embryos at 10 to 12 weeks of gestation. Of these, 13 were delivered at medical abortions from healthy women, and 7 from women with 2nd stage alcoholism. In both groups the electron-dense structures were shown in the perinuclear space of neuro- and glioblasts. In embryos taken from alcoholic mothers, these cells displayed the changes in plasma and mitochondrial membranes structure with appearing inclusions and enhanced development of several organels. The data on ultrastructural changes in alcoholic brain embryonic cells are compared to those in other maternal mental disorders.

摘要

对20例妊娠10至12周的人类胚胎的脑细胞进行了电子显微镜检查。其中,13例来自健康女性的人工流产,7例来自患有二期酒精中毒的女性。在两组中,神经母细胞和胶质母细胞的核周间隙均显示出电子致密结构。在取自酗酒母亲的胚胎中,这些细胞的质膜和线粒体膜结构出现变化,伴有包涵体出现,且几种细胞器发育增强。将酒精性脑胚胎细胞超微结构变化的数据与其他母体精神障碍中的数据进行了比较。

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[Lamellar formations in the brain cells of embryos of schizophrenic mothers].
Zh Nevropatol Psikhiatr Im S S Korsakova. 1980;80(7):1055-8.
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[Ultrastructural localization of cytochrome oxidase in human embryonic brain cells].
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