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[酒精性胚胎病中的小脑发育障碍]

[Disorders of the cerebellar development in alcoholic embryopathy].

作者信息

Kovetskiĭ N S

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1989;89(7):45-9.

PMID:2800811
Abstract

A total of 38 embryos were delivered at abortions from women which had abused alcohol during gestation (5 to 12 weeks). Defects of cerebellar development were found in 8 cases (21%). In I case the cerebellar rudiment agenesia was noted. In 7 cases cerebellar hemispheres featured dysmorphogenic changes. Of these, in 2 the rudiments of left cerebellar hemispheres were hyperplastic and located deep in the cavity of the IVth ventricle; in the rest, extra plicate and circular formations were found in preparations with and without hyperplasia.

摘要

共有38个胚胎取自孕期(5至12周)酗酒的女性流产胎儿。其中8例(21%)发现小脑发育缺陷。1例为小脑原基发育不全。7例小脑半球有形态发生异常改变。其中,2例左小脑半球原基增生并位于第四脑室腔内深处;其余病例中,无论有无增生,标本中均发现有额外的褶皱和环状结构。

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