Mzhe'lskaia T I, Larskiĭ E G, Pashchenko L A, Gladkikh S P, Ivanova-Smolenskaia I A, Markova E D
Zh Nevropatol Psikhiatr Im S S Korsakova. 1989;89(7):69-73.
In a patients with extrapyramidal-cortical form of the Wilson-Konovalov disease, brain and liver tissues were tested for Ca, Cu, Fe, Ka, Mg, Mn, Mo, P, Pb, Se, Sn, Sz, Zn, S, using plasma emission spectrometry. The tissues autopsied from 2 cerebral hemorrhage victims served as controls. Hepatic Cu concentration was increased 24-fold (6.89 mumole/g of tissue dry weight); Cu accumulation in the brain cortex and basal ganglia were 10 times as high as control levels; hepatic (8.78 mumole/g) and brain cortical (2.23 mumole/g) Zn contents were higher than controls, respectively by factors of 2 and 1.7; hepatic S content (289.4 mumole/g) was 1.2 times the control level; Mn brain content was above the control value. Mg was below the appreciable amount in the brain that was not the case in control. On the contrary, Sr was detected only in basal ganglia and liver in the patient and not detected in control tissues. Pb content in the patient's liver was above the control level.
在一名患有威尔逊 - 科诺瓦洛夫病锥体外系 - 皮质型的患者中，使用等离子体发射光谱法对其脑和肝组织进行了钙（Ca）、铜（Cu）、铁（Fe）、钾（Ka）、镁（Mg）、锰（Mn）、钼（Mo）、磷（P）、铅（Pb）、硒（Se）、锡（Sn）、锶（Sz）、锌（Zn）、硫（S）检测。取自2名脑出血受害者的尸检组织用作对照。肝脏铜浓度增加了24倍（6.89微摩尔/克组织干重）；大脑皮质和基底神经节中的铜积累量是对照水平的10倍；肝脏（8.78微摩尔/克）和大脑皮质（2.23微摩尔/克）的锌含量分别比对照高2倍和1.7倍；肝脏硫含量（289.4微摩尔/克）是对照水平的1.2倍；脑中锰含量高于对照值。脑中镁含量低于可检测量，而对照中并非如此。相反，仅在患者的基底神经节和肝脏中检测到锶，对照组织中未检测到。患者肝脏中的铅含量高于对照水平。
