[甲状腺毒症患者肌病发病机制的各种问题]

[Various problems of the pathogenesis of myopathy in patients with thyrotoxicosis].

作者信息

Kazakov V M, Skoromets A A

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1989;89(7):73-9.

Abstract

In patients with thyrotoxic myopathy, histological investigation showed the decrease in mean diameter of skeletal muscles, and increased collateral branching of distal axons. The percentage of afflicted fibers was not high with focal pathology. The signs of true reinnervation were absent. Electroneuromyographic investigation confirmed mild myopathy. The authors discuss the possible participation of cyclic nucleotide system disorders in muscular weakness in these patients.

摘要

在甲状腺毒症性肌病患者中，组织学检查显示骨骼肌平均直径减小，远端轴突侧支分支增加。受累纤维的百分比不高，存在局灶性病变。无真正神经再支配的迹象。神经肌电图检查证实为轻度肌病。作者讨论了环核苷酸系统紊乱在这些患者肌肉无力中可能起的作用。