Vaidyanathan Subramanian, Oo Tun, Soni Bakul M, Hughes Peter L, Singh Gurpreet
Regional Spinal Injuries Centre, Southport and Formby District General Hospital, Southport, UK.
Department of Radiology, Southport and Formby District General Hospital, Southport, UK.
Clin Med Insights Case Rep. 2016 Dec 13;9:119-121. doi: 10.4137/CCRep.S39117. eCollection 2016.
Intrathecal administration of baclofen by implanted pump reduces rigidity and muscle spasms. Its use specifically to control bladder spasms has not been reported.
A tetraplegic patient developed severe, protracted, bladder spasms, abdominal muscles spasms, and high blood pressure after change of suprapubic catheter; nifedipine, diazepam, and paracetamol did not control spasms; bolus dose of baclofen intrathecally produced prompt relief via baclofen pump.
Severe, protracted bladder spasms, abdominal muscles spasms, and autonomic dysreflexia, induced by change of suprapubic catheter in a spinal cord injury patient, were treated successfully by a bolus dose and increased total daily dose of intrathecal baclofen.
通过植入泵鞘内注射巴氯芬可减轻僵硬和肌肉痉挛。其专门用于控制膀胱痉挛的情况尚未见报道。
一名四肢瘫痪患者在耻骨上导尿管更换后出现严重、持续性膀胱痉挛、腹部肌肉痉挛和高血压；硝苯地平、地西泮和对乙酰氨基酚未能控制痉挛；鞘内注射大剂量巴氯芬通过巴氯芬泵迅速缓解症状。
脊髓损伤患者因耻骨上导尿管更换引起的严重、持续性膀胱痉挛、腹部肌肉痉挛和自主神经反射异常，通过鞘内注射大剂量巴氯芬并增加每日总剂量得到成功治疗。
