Nevelsteen A, Beyens G, Smet G, Suy R
Department of Vascular Surgery, UZ Gasthuisberg-St. Rafael, Leuven, België.
Acta Chir Belg. 1989 Jul-Aug;89(4):179-84.
A prospective study was undertaken to evaluate the clinical and hemodynamic effects of aortofemoral Dacron reconstruction in patients with multilevel disease (i.e. aortoiliac and femoropopliteal occlusive disease). Thirty nine patients underwent, apart from clinical evaluation, segmental plethysmography and Doppler pressures before operation, immediately after operation and again at 3 and 6 months. All patients improved by the reconstruction, but 12 (31%) continued to complain of disabling claudication during normal daily activities. The mean ankle pressure and thigh pressure index improved by 37.5%. This was accompanied by a decrease of peak flow time, an increase of peak flow and an improved recovery during reactive hyperemia. Furthermore an additional significant rise of the ankle pressure index was noted between 3 and 6 months. Continuing claudication was always associated with both initial and late hemodynamic failure (the criterium for hemodynamic success was defined as an increase of the ankle pressure index with more than 0.1). Hemodynamic success resulted unvariably in clinical success. However 4 patients were clinically symptomfree, although they had to be classified as hemodynamic failures. It is concluded that a significant number of patients fail to obtain complete relief after proximal reconstruction. Preoperative hemodynamic studies may provide additional information, but hemodynamic and clinical results do not always correlate with each other.
一项前瞻性研究旨在评估主动脉股动脉涤纶血管重建术对患有多节段疾病(即主髂动脉和股腘动脉闭塞性疾病)患者的临床和血流动力学影响。39例患者除了接受临床评估外,还在术前、术后即刻以及术后3个月和6个月进行了节段性体积描记法和多普勒压力测量。所有患者经重建术后病情均有改善,但12例(31%)患者在日常活动中仍主诉有致残性间歇性跛行。平均踝压和大腿压力指数提高了37.5%。这伴随着峰值血流时间缩短、峰值血流增加以及反应性充血期间恢复情况改善。此外,在3至6个月期间还观察到踝压指数有额外的显著升高。持续性间歇性跛行总是与初始和晚期血流动力学失败相关(血流动力学成功的标准定义为踝压指数增加超过0.1)。血流动力学成功始终导致临床成功。然而,有4例患者临床无症状,尽管他们必须被归类为血流动力学失败。得出的结论是,相当数量的患者在近端重建术后未能获得完全缓解。术前血流动力学研究可能会提供更多信息,但血流动力学和临床结果并不总是相互关联的。