约旦年轻单峰驼中存在高比例的中东呼吸综合征冠状病毒。
High Prevalence of Middle East Respiratory Coronavirus in Young Dromedary Camels in Jordan.
机构信息
1 Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health , Hamilton, Montana.
2 Food and Agriculture Organization of the United Nations (FAO) , Amman, Jordan .
出版信息
Vector Borne Zoonotic Dis. 2017 Feb;17(2):155-159. doi: 10.1089/vbz.2016.2062. Epub 2016 Dec 23.
Abstract
Prevalence of Middle East respiratory syndrome coronavirus (MERS-CoV) was determined in 45 dromedary camels from two geographically separated herds in Jordan. Virus shedding was only detected in swabs obtained from the respiratory tract and primarily observed in camels younger than 3 years. MERS-CoV seroprevalence increased with age of camels. Bovine and sheep sera were seronegative. Phylogenetic analysis of partial S2 clustered the Jordanian MERS-CoV strains with contemporary MERS-CoV strains associated with nosocomial outbreaks.
摘要
在对来自约旦两个地理位置分隔的骆驼群的 45 头单峰驼进行检测后，发现了中东呼吸综合征冠状病毒（MERS-CoV）。仅从呼吸道拭子中检测到病毒脱落，并且主要在年龄小于 3 岁的骆驼中观察到。MERS-CoV 的血清阳性率随着骆驼年龄的增长而增加。牛和绵羊血清均为血清阴性。S2 部分的系统发育分析将约旦的 MERS-CoV 株与与医院感染暴发相关的当代 MERS-CoV 株聚类在一起。
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