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Time Course of MERS-CoV Infection and Immunity in Dromedary Camels.单峰骆驼中东呼吸综合征冠状病毒感染与免疫的时间进程
Emerg Infect Dis. 2016 Dec;22(12):2171-2173. doi: 10.3201/eid2212.160382. Epub 2016 Dec 15.
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Deletion Variants of Middle East Respiratory Syndrome Coronavirus from Humans, Jordan, 2015.2015年约旦人类中东呼吸综合征冠状病毒的缺失变异体
Emerg Infect Dis. 2016 Apr;22(4):716-9. doi: 10.3201/eid2204.152065.
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Cross host transmission in the emergence of MERS coronavirus.中东呼吸综合征冠状病毒出现过程中的跨宿主传播
Curr Opin Virol. 2016 Feb;16:55-62. doi: 10.1016/j.coviro.2016.01.004. Epub 2016 Jan 29.
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High proportion of MERS-CoV shedding dromedaries at slaughterhouse with a potential epidemiological link to human cases, Qatar 2014.2014年卡塔尔,屠宰场中中东呼吸综合征冠状病毒(MERS-CoV)高比例排毒的单峰骆驼与人类病例存在潜在流行病学关联。
Infect Ecol Epidemiol. 2015 Jul 15;5:28305. doi: 10.3402/iee.v5.28305. eCollection 2015.
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Reliable typing of MERS-CoV variants with a small genome fragment.利用小基因组片段对中东呼吸综合征冠状病毒(MERS-CoV)变体进行可靠分型
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Human infection with MERS coronavirus after exposure to infected camels, Saudi Arabia, 2013.2013年,沙特阿拉伯,人类在接触感染的骆驼后感染中东呼吸综合征冠状病毒。
Emerg Infect Dis. 2014 Jun;20(6):1012-5. doi: 10.3201/eid2006.140402.
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Middle East respiratory syndrome coronavirus in dromedary camels: an outbreak investigation.中东呼吸综合征冠状病毒在单峰驼中的流行情况:暴发调查。
Lancet Infect Dis. 2014 Feb;14(2):140-5. doi: 10.1016/S1473-3099(13)70690-X. Epub 2013 Dec 17.
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Middle East Respiratory Syndrome coronavirus (MERS-CoV) serology in major livestock species in an affected region in Jordan, June to September 2013.2013 年 6 月至 9 月,在约旦受影响地区对主要牲畜物种中的中东呼吸综合征冠状病毒(MERS-CoV)进行血清学检测。
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9
Novel coronavirus infections in Jordan, April 2012: epidemiological findings from a retrospective investigation.2012 年 4 月在约旦的新型冠状病毒感染:回顾性调查的流行病学结果。
East Mediterr Health J. 2013;19 Suppl 1:S12-8.
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Assays for laboratory confirmation of novel human coronavirus (hCoV-EMC) infections.新型人类冠状病毒(hCoV-EMC)感染的实验室确诊检测方法。
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约旦年轻单峰驼中存在高比例的中东呼吸综合征冠状病毒。

High Prevalence of Middle East Respiratory Coronavirus in Young Dromedary Camels in Jordan.

机构信息

1 Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health , Hamilton, Montana.

2 Food and Agriculture Organization of the United Nations (FAO) , Amman, Jordan .

出版信息

Vector Borne Zoonotic Dis. 2017 Feb;17(2):155-159. doi: 10.1089/vbz.2016.2062. Epub 2016 Dec 23.

DOI:10.1089/vbz.2016.2062
PMID:28009529
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5278817/
Abstract

Prevalence of Middle East respiratory syndrome coronavirus (MERS-CoV) was determined in 45 dromedary camels from two geographically separated herds in Jordan. Virus shedding was only detected in swabs obtained from the respiratory tract and primarily observed in camels younger than 3 years. MERS-CoV seroprevalence increased with age of camels. Bovine and sheep sera were seronegative. Phylogenetic analysis of partial S2 clustered the Jordanian MERS-CoV strains with contemporary MERS-CoV strains associated with nosocomial outbreaks.

摘要

在对来自约旦两个地理位置分隔的骆驼群的 45 头单峰驼进行检测后,发现了中东呼吸综合征冠状病毒(MERS-CoV)。仅从呼吸道拭子中检测到病毒脱落,并且主要在年龄小于 3 岁的骆驼中观察到。MERS-CoV 的血清阳性率随着骆驼年龄的增长而增加。牛和绵羊血清均为血清阴性。S2 部分的系统发育分析将约旦的 MERS-CoV 株与与医院感染暴发相关的当代 MERS-CoV 株聚类在一起。