Chowdhury Enayet K, Nelson Mark R, Jennings Garry L R, Wing Lindon M H, Reid Christopher M
aCentre of Cardiovascular Research & Education in Therapeutics, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria bMenzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania cBaker IDI Heart and Diabetes Institute, Melbourne, Victoria dSchool of Medicine, Flinders University, Adelaide, South Australia eSchool of Public Health, Curtin University, Perth, Western Australia, Australia.
J Hypertens. 2017 Apr;35(4):769-775. doi: 10.1097/HJH.0000000000001214.
To assess the association of pet ownership and all-cause and cardiovascular mortality over a long-term follow-up among elderly treated hypertensive participants.
Pet-ownership data from a subcohort of the Second Australian National Blood Pressure study were used. Participants were aged 65-84 years at enrolment (1995-1997) and responded to a pet-ownership questionnaire during year 2000. Participants' survival information was determined over a median of 10.9 years that includes Second Australian National Blood Pressure in-trial period (median 4.2 years) together with posttrial follow-up period (median 6.9 years). For the current study, end points were any fatal cardiovascular event and all-cause fatal events.
Of those who responded to a pet-ownership questionnaire (4039/6018 - 67%), 86% (3490/4039) owned at least one pet at any-time during their life (current or previous pet owner), with 36% (1456/4039) owning at least one pet at the time of the survey. During the follow-up period, 958 participants died including 499 deaths of cardiovascular origin. Using a Cox proportional hazard regression model adjusting for possible confounders, there was a 22 and 26% reduction in cardiovascular mortality observed among previous and current pet owners, respectively, compared with those who had never owned one. A similar nonsignificant trend was observed for all-cause mortality once adjusted for potential confounders.
Pet ownership was associated with an improved cardiovascular disease survival in a treated elderly hypertensive population.
评估在接受治疗的老年高血压参与者的长期随访中，养宠物与全因死亡率和心血管死亡率之间的关联。
使用了来自第二项澳大利亚全国血压研究亚队列的养宠物数据。参与者在入组时（1995 - 1997年）年龄为65 - 84岁，并在2000年回答了一份养宠物问卷。参与者的生存信息在中位时间为10.9年的期间内确定，这包括澳大利亚全国血压研究的试验期（中位时间4.2年）以及试验后的随访期（中位时间6.9年）。对于本研究，终点是任何致命性心血管事件和全因致命事件。
在回答养宠物问卷的人中（4039/6018 - 67%），86%（3490/4039）在其一生中的任何时候都拥有至少一只宠物（当前或以前的宠物主人），其中36%（1456/4039）在调查时拥有至少一只宠物。在随访期间，958名参与者死亡，其中499例死于心血管疾病。使用Cox比例风险回归模型对可能的混杂因素进行调整后，与从未养过宠物的人相比，以前和当前的宠物主人的心血管死亡率分别降低了22%和26%。在对潜在混杂因素进行调整后，全因死亡率也观察到类似的非显著趋势。
在接受治疗的老年高血压人群中，养宠物与心血管疾病生存率的提高有关。
