Asbjørn J, Jakobsen B W, Pilegaard H K, Blom L, Ostergaard A, Brandt M R
Department of Anaesthesiology, Central Hospital, Holstebro, Denmark.
Acta Anaesthesiol Scand. 1989 Jul;33(5):369-73. doi: 10.1111/j.1399-6576.1989.tb02925.x.
To evaluate whether there is a difference in mental function after general anaesthesia and epidural analgesia, a homogeneous group of 40 elderly men (age between 60 and 80) undergoing transurethral prostatectomy was studied. The study was prospective, randomised and double blind. Patients with all types of complications believed to impair mental function were excluded. Long-term, short-term, verbal and visual memory were tested preoperatively, and 4 days, and 3 weeks postoperatively. In conclusion, we found a significant and equal decline in test performance on the fourth postoperative day. Three weeks postoperatively, however, both groups had returned to or exceeded preoperative levels of performance.
为评估全身麻醉和硬膜外镇痛后心理功能是否存在差异,我们对40名年龄在60至80岁之间接受经尿道前列腺切除术的老年男性组成的同质组进行了研究。该研究为前瞻性、随机和双盲研究。排除所有被认为会损害心理功能的并发症患者。术前、术后4天和3周对长期、短期、言语和视觉记忆进行了测试。总之,我们发现在术后第四天测试表现有显著且同等程度的下降。然而,术后三周,两组均恢复到或超过了术前的表现水平。