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老年男性术后硬膜外镇痛期间的心理功能

Mental function in elderly men after surgery during epidural analgesia.

作者信息

Asbjørn J, Jakobsen B W, Pilegaard H K, Blom L, Ostergaard A, Brandt M R

机构信息

Department of Anaesthesiology, Central Hospital, Holstebro, Denmark.

出版信息

Acta Anaesthesiol Scand. 1989 Jul;33(5):369-73. doi: 10.1111/j.1399-6576.1989.tb02925.x.

DOI:10.1111/j.1399-6576.1989.tb02925.x
PMID:2800973
Abstract

To evaluate whether there is a difference in mental function after general anaesthesia and epidural analgesia, a homogeneous group of 40 elderly men (age between 60 and 80) undergoing transurethral prostatectomy was studied. The study was prospective, randomised and double blind. Patients with all types of complications believed to impair mental function were excluded. Long-term, short-term, verbal and visual memory were tested preoperatively, and 4 days, and 3 weeks postoperatively. In conclusion, we found a significant and equal decline in test performance on the fourth postoperative day. Three weeks postoperatively, however, both groups had returned to or exceeded preoperative levels of performance.

摘要

为评估全身麻醉和硬膜外镇痛后心理功能是否存在差异,我们对40名年龄在60至80岁之间接受经尿道前列腺切除术的老年男性组成的同质组进行了研究。该研究为前瞻性、随机和双盲研究。排除所有被认为会损害心理功能的并发症患者。术前、术后4天和3周对长期、短期、言语和视觉记忆进行了测试。总之,我们发现在术后第四天测试表现有显著且同等程度的下降。然而,术后三周,两组均恢复到或超过了术前的表现水平。

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引用本文的文献

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Postoperative cognitive function following general versus regional anesthesia: a systematic review.全麻与区域麻醉对术后认知功能的影响:系统综述。
J Neurosurg Anesthesiol. 2014 Oct;26(4):369-76. doi: 10.1097/ANA.0000000000000120.
2
General anaesthesia does not contribute to long-term post-operative cognitive dysfunction in adults: A meta-analysis.全身麻醉不会导致成人术后长期认知功能障碍:一项荟萃分析。
Indian J Anaesth. 2011 Jul;55(4):358-63. doi: 10.4103/0019-5049.84850.
3
The role of epidural anesthesia and analgesia in surgical practice.
硬膜外麻醉与镇痛在外科手术中的作用。
Ann Surg. 2003 Nov;238(5):663-73. doi: 10.1097/01.sla.0000094300.36689.ad.
4
Postoperative cognitive dysfunction versus complaints: a discrepancy in long-term findings.术后认知功能障碍与术后不适:长期研究结果中的差异
Neuropsychol Rev. 2002 Mar;12(1):1-14. doi: 10.1023/a:1015404122161.
5
Reduction of postoperative mortality and morbidity with epidural or spinal anaesthesia: results from overview of randomised trials.硬膜外或脊髓麻醉降低术后死亡率和发病率:随机试验综述结果
BMJ. 2000 Dec 16;321(7275):1493. doi: 10.1136/bmj.321.7275.1493.
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Regional vs general anaesthesia in orthopaedics.骨科手术中的区域麻醉与全身麻醉
Can J Anaesth. 1993 May;40(5 Pt 2):R104-12. doi: 10.1007/BF03020690.