Kang Kyung A, Maldonado Claudio, Vodyanoy Vitaly
Department of Chemical Engineering, University of Louisville, Louisville, KY, USA.
Department of Physiology and Biophysics, University of Louisville, Louisville, KY, USA.
J Acupunct Meridian Stud. 2016 Dec;9(6):297-306. doi: 10.1016/j.jams.2016.02.001. Epub 2016 Feb 17.
Since Bonghan Kim's discovery of the Bonghan system (BHS) in the 1960s, numerous reports have suggested that the system is fundamental for maintaining mammalian life. The BHS is a circulatory system independent of the blood or the lymphatic system, forms an extensive network throughout the entire mammalian body, has been reported to be the acupuncture meridian, stores distinct types of stem cells, and appears to have some roles in cancer metastasis. Despite Kim's first report having been published as early as 1962, research progress has been rather slow mainly because the system is very small and translucent, making it optically difficult to distinguish it from the hemoglobin-rich surrounding tissues. Unfortunately, Kim did not describe in detail the methods that he used for identifying and harvesting the system and the components of the system. In 2000, Kwang-Sup Soh reopened the BHS research, and since then, new and important scientific findings on the system have been reported, and many of Kim's results have been verified. In 2010, the BHS was renamed the primo vascular system. Nevertheless, good tools to properly deal with this system are still lacking. In this article, we address some of the technical difficulties involved in studying the primo vascular system and attempt to discuss potential ways to overcome those difficulties.
自20世纪60年代奉韩金发现奉韩系统(BHS)以来,大量报告表明该系统是维持哺乳动物生命的基础。BHS是一个独立于血液或淋巴系统的循环系统,在整个哺乳动物体内形成广泛的网络,据报道是经络,储存不同类型的干细胞,并且似乎在癌症转移中发挥一些作用。尽管金早在1962年就发表了第一篇报告,但研究进展相当缓慢,主要是因为该系统非常小且半透明,从光学上很难将其与富含血红蛋白的周围组织区分开来。不幸的是,金没有详细描述他用于识别和获取该系统及其组成部分的方法。2000年,Kwang-Sup Soh重新开启了BHS研究,从那时起,关于该系统的新的重要科学发现不断被报道,金的许多结果也得到了验证。2010年,BHS被重新命名为原始血管系统。然而,仍然缺乏妥善处理该系统的良好工具。在本文中,我们阐述了研究原始血管系统所涉及的一些技术难题,并试图探讨克服这些难题的潜在方法。