Department of Obstetrics and Gynaecology, Máxima Medical Centre, Veldhoven, The Netherlands.
Department of Obstetrics and Gynaecology, Academic Medical Centre, Amsterdam, The Netherlands.
BJOG. 2017 Jan;124(2):190-199. doi: 10.1111/1471-0528.14395.
Endometrial ablation has been widely implemented in the outpatient setting. Many different protocols of local anaesthesia during endometrial ablation are used and described. However, prospective studies to assess and evaluate these protocols appear to be scarce.
To evaluate systematically the different local anaesthesia techniques in relation to pain perception during endometrial ablation.
Medline and Embase were systematically searched and reference lists of selected articles were checked for missed publications.
All types of studies reporting the performance of endometrial ablation under local anaesthesia in ten or more women were included.
Data about the procedure, the protocol of local anaesthesia, the acceptability and side-effects were extracted.
Twenty-five studies, involving 2013 women, were included. Applied anaesthesia techniques included intracervical, paracervical and intrauterine anaesthesia or a combination of these techniques. Women who received a combination of either intra- or paracervical anaesthesia and intrauterine injections reported significantly lower pain scores than those who received no local anaesthesia or intra- or paracervical anaesthesia alone (P = 0.000), but the quality of evidence is low. The acceptability of endometrial ablation under local anaesthesia was high (77-94%).
Endometrial ablation under local anaesthesia is a safe, feasible and acceptable procedure. The combination of either intra- or paracervical anaesthesia with intrauterine injections seems to be promising, but has to be investigated more thoroughly.
Systematic review of local anaesthesia techniques during endometrial ablation.
子宫内膜消融术已在门诊广泛开展。许多不同的局部麻醉方案在子宫内膜消融术中被使用和描述。然而,评估和评估这些方案的前瞻性研究似乎很少。
系统评估不同的局部麻醉技术与子宫内膜消融过程中的疼痛感知的关系。
系统检索了 Medline 和 Embase,并检查了选定文章的参考文献列表,以查找遗漏的出版物。
所有报告在 10 名或更多女性中进行子宫内膜消融术的局部麻醉的研究类型均被纳入。
提取了有关程序、局部麻醉方案、可接受性和副作用的数据。
纳入了 25 项研究,涉及 2013 名女性。应用的麻醉技术包括宫颈内、宫颈旁和子宫内麻醉,或这些技术的联合应用。接受宫颈内或宫颈旁麻醉联合子宫内注射的女性报告的疼痛评分明显低于未接受局部麻醉或仅接受宫颈内或宫颈旁麻醉的女性(P=0.000),但证据质量较低。在局部麻醉下进行子宫内膜消融术的可接受性很高(77-94%)。
在局部麻醉下进行子宫内膜消融术是一种安全、可行且可接受的方法。宫颈内或宫颈旁麻醉联合子宫内注射似乎很有前途,但需要更深入地研究。