Bowling Green State University, School of Human Movement, Sport and Leisure Studies, Bowling Green, OH 43403, USA; School of Public Health, Tropical Medicine and Rehabilitation Sciences, James Cook University, Townsville, Qld, Australia.
Institute of Occupational and Social Medicine, RWTH Aachen Technical University, Pauwelsstr. 30, D-52074 Aachen, Germany.
Travel Med Infect Dis. 2017 Mar-Apr;16:49-51. doi: 10.1016/j.tmaid.2016.12.005. Epub 2016 Dec 22.
Naegleria fowleri is a deadly human pathogen recognized as the causative agent of Primary Amoebic Meningitis (PAM). N. fowleri is commonly found in warm freshwater environments such as natural or man-made lakes, hot springs, and resort spas frequented by tourists. PAM infections have a mortality rate between 95 and 99% with minimal progress being made toward a successful treatment therapy. We report the case of a 12-year old American female who survived a PAM infection and propose a new drug therapy which includes the antimicrobial drug Miltefosine.
福氏耐格里阿米巴是一种致命的人类病原体，被认为是原发性阿米巴脑膜脑炎（PAM）的病原体。福氏耐格里阿米巴常见于温暖的淡水环境中，如自然或人工湖泊、温泉和游客常去的度假胜地温泉。PAM 感染的死亡率在 95%到 99%之间，目前在成功的治疗方法方面进展甚微。我们报告了一例 12 岁美国女性 PAM 感染存活的病例，并提出了一种新的药物治疗方法，包括抗菌药物米替福新。
