Instituto de Medicina Tropical "Alexander Von Humboldt", Universidad Peruana Cayetano Heredia, Lima, Perú.
Departamento de Enfermedades Infecciosas, Tropicales y Dermatológicas, Hospital Cayetano Heredia, Lima, Perú.
Acta Parasitol. 2022 Sep;67(3):1421-1424. doi: 10.1007/s11686-022-00591-9. Epub 2022 Jul 21.
The genus Naegleria consists of free-living amoebae widely distributed worldwide in soil and freshwater habitats. Primary amoebic meningoencephalitis (PAM) is an uncommon and most likely fatal disease. The incubation period is approximately 7 days. The first symptoms are headache, nasal congestion, fever, vomiting, stiff neck within 3-4 days after the first symptoms, confusion, abnormal behavior, seizures, loss of balance and body control, coma, and death. We describe the case of a child who presented with PAM due to Naegleria sp., fully recovered from the infection without apparent sequels after treatment with a regimen that included miltefosine and voriconazole.
纳格尔里亚属是一种自由生活的变形虫，广泛分布于世界各地的土壤和淡水栖息地。原发性阿米巴脑膜脑炎（PAM）是一种罕见且极有可能致命的疾病。潜伏期约为 7 天。最初的症状是头痛、鼻塞、发热、呕吐，最初症状出现后 3-4 天内出现颈部僵硬、意识模糊、行为异常、癫痫发作、失去平衡和身体控制、昏迷和死亡。我们描述了一例因纳格尔里亚属引起的 PAM 的儿童病例，该患儿在接受米替福新和伏立康唑治疗后完全康复，没有明显后遗症。
