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肾细胞癌骨转移的临床研究:与肺转移的对比研究

[Clinical study of renal cell carcinoma with bony metastasis: comparative study with lung metastasis].

作者信息

Onishi T, Machida T, Masuda F, Suzuki M, Iizuka N, Nakauchi K, Suzuki H

机构信息

Department of Urology, Jikei University School of Medicine.

出版信息

Hinyokika Kiyo. 1989 Jul;35(7):1113-8.

PMID:2801402
Abstract

For the purpose of clinical analysis of renal cell carcinoma with bony metastasis (59 cases) the cases with lung metastasis (146 cases) were selected for comparison. The analyzed items were the distribution of bony metastatic portions, the results of radiotherapy for bony metastasis, comparative study with lung metastasis on clinical background, comparative study with lung and bony metastasis on the survival rate, comparative study with solitary bony and lung metastasis on the survival rate, comparative study with bony and lung metastasis on the grade of primary lesion. The most frequent metastatic portion was lower extremities, spine, upper extremities and pelvic bone in this order. The survival rate of the cases with bony metastasis was better than that of lung, especially with solitary metastatic cases. The effects of radiotherapy for bony metastasis were not so good for prolonging the survival. The grade of kidney malignancy did not influence the survival of patients with bony metastasis, on the contrary, in patients with lung metastasis, there was a good prognostic factor for survival.

摘要

为了对伴有骨转移的肾细胞癌患者(59例)进行临床分析,选取了伴有肺转移的患者(146例)作为对照。分析项目包括骨转移部位的分布、骨转移的放疗结果、骨转移与肺转移在临床背景方面的对比研究、骨转移与肺转移在生存率方面的对比研究、孤立性骨转移与肺转移在生存率方面的对比研究、骨转移与肺转移在原发灶分级方面的对比研究。最常见的转移部位依次为下肢、脊柱、上肢和骨盆。骨转移患者的生存率高于肺转移患者,尤其是孤立性转移病例。骨转移放疗对延长生存期的效果不佳。肾恶性肿瘤分级不影响骨转移患者的生存,相反,在肺转移患者中,存在一个良好的生存预后因素。

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