高阴离子间隙代谢性酸中毒速览

A Quick Reference on High Anion Gap Metabolic Acidosis.

作者信息

Funes Silvia, de Morais Helio Autran

机构信息

Department of Clinical Sciences, College of Veterinary Medicine, Oregon State University, 700 Southwest 30th Street, Corvallis, OR 97331, USA.

出版信息

Vet Clin North Am Small Anim Pract. 2017 Mar;47(2):205-207. doi: 10.1016/j.cvsm.2016.11.002. Epub 2016 Dec 23.

DOI:10.1016/j.cvsm.2016.11.002

PMID:28017408

Abstract

High anion gap (AG) metabolic acidoses can be identified by a decrease in pH, decrease in HCO or base excess, and an increased AG. The AG represents the difference between unmeasured cations and unmeasured anions; it increases secondary to the accumulation of anions other than bicarbonate and chloride. The most common causes of high AG acidosis are renal failure, diabetic ketoacidosis, and lactic acidosis. Severe increases in concentration of phosphorus can cause hyperphosphatemic acidosis.

摘要

高阴离子间隙（AG）代谢性酸中毒可通过pH值降低、碳酸氢根（HCO）或碱剩余降低以及AG升高来识别。AG代表未测定阳离子与未测定阴离子之间的差值；它因碳酸氢根和氯离子以外的阴离子蓄积而继发性升高。高AG酸中毒最常见的病因是肾衰竭、糖尿病酮症酸中毒和乳酸酸中毒。磷浓度严重升高可导致高磷血症性酸中毒。