Burgos Rosilene C Rossetto, van Wijk Eduard P A, van Wijk Roeland, He Min, van der Greef Jan
Division of Analytical Biosciences, Leiden Academic Center for Drug Research, Leiden UniversityLeiden, Netherlands; Sino-Dutch Center for Preventive and Personalized Medicine/Center for Photonics of Living Systems, Leiden UniversityLeiden, Netherlands.
Division of Analytical Biosciences, Leiden Academic Center for Drug Research, Leiden UniversityLeiden, Netherlands; Sino-Dutch Center for Preventive and Personalized Medicine/Center for Photonics of Living Systems, Leiden UniversityLeiden, Netherlands; Meluna Research in BiophotonicsGeldermalsen, Netherlands.
Front Physiol. 2016 Dec 15;7:611. doi: 10.3389/fphys.2016.00611. eCollection 2016.
The current healthcare system is hampered by a reductionist approach in which diagnostics and interventions focus on a specific target, resulting in medicines that center on generic, static phenomena while excluding inherent dynamic nature of biological processes, let alone psychosocial parameters. In this essay, we present some limitations of the current healthcare system and introduce the novel and potential approach of combining ultra-weak photon emission (UPE) with metabolomics technology in order to provide a dynamic readout of higher organizational systems. We argue that the combination of metabolomics and UPE can bring a new, broader, view of health state and can potentially help to shift healthcare toward more personalized approach that improves patient well-being.
当前的医疗保健系统受到还原论方法的阻碍，在这种方法中，诊断和干预集中于特定目标，导致药物以一般的、静态的现象为中心，却排除了生物过程固有的动态性质，更不用说心理社会参数了。在本文中，我们阐述了当前医疗保健系统的一些局限性，并介绍了将超弱光子发射（UPE）与代谢组学技术相结合的新颖且具有潜力的方法，以便对更高层次的组织系统进行动态读数。我们认为，代谢组学和UPE的结合可以带来关于健康状态的全新、更广泛的视角，并有可能帮助推动医疗保健向更个性化的方法转变，从而提高患者的幸福感。
