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阵发性心房颤动患者行导管消融时的房间阻滞及房间隔厚度:长期随访研究

Interatrial block and interatrial septal thickness in patients with paroxysmal atrial fibrillation undergoing catheter ablation: Long-term follow-up study.

作者信息

Gul Enes E, Pal Raveen, Caldwell Jane, Boles Usama, Hopman Wilma, Glover Benedict, Michael Kevin A, Redfearn Damian, Simpson Chris, Abdollah Hoshiar, Baranchuk Adrian

机构信息

Heart Rhythm Service, Kingston General Hospital, Queen's University, Kingston, ON, Canada.

Department of Cardiology, Kingston General Hospital, Queen's University, Kingston, ON, Canada.

出版信息

Ann Noninvasive Electrocardiol. 2017 Jul;22(4). doi: 10.1111/anec.12428. Epub 2016 Dec 25.

Abstract

BACKGROUND

Interatrial block (IAB) is a strong predictor of recurrence of atrial fibrillation (AF). IAB is a conduction delay through the Bachman region, which is located in the upper region of the interatrial space. During IAB, the impulse travels from the right atrium to the interatrial septum (IAS) and coronary sinus to finally reach the left atrium in a caudocranial direction. No relation between the presence of IAB and IAS thickness has been established yet.

OBJECTIVE

To determine whether a correlation exists between the degree of IAB and the thickness of the IAS and to determine whether IAS thickness predicts AF recurrence.

METHODS

Sixty-two patients with diagnosis of paroxysmal AF undergoing catheter ablation were enrolled. IAB was defined as P-wave duration ≥120 ms. IAS thickness was measured by cardiac computed tomography.

RESULTS

Among 62 patients with paroxysmal AF, 45 patients (72%) were diagnosed with IAB. Advanced IAB was diagnosed in 24 patients (39%). Forty-seven patients were male. During a mean follow-up period of 49.8 ± 22 months (range 12-60 months), 32 patients (51%) developed AF recurrence. IAS thickness was similar in patients with and without IAB (4.5 ± 2.0 mm vs. 4.0 ± 1.4 mm; p = .45) and did not predict AF. Left atrial size was significantly enlarged in patients with IAB (40.9 ± 5.7 mm vs. 37.2 ± 4.0 mm; p = .03). Advanced IAB predicted AF recurrence after the ablation (OR: 3.34, CI: 1.12-9.93; p = .03).

CONCLUSIONS

IAS thickness was not significantly correlated to IAB and did not predict AF recurrence. IAB as previously demonstrated was an independent predictor of AF recurrence.

摘要

背景

房间阻滞(IAB)是心房颤动(AF)复发的有力预测指标。IAB是通过位于房间隔上部区域的巴赫曼区域的传导延迟。在IAB期间,冲动从右心房传至房间隔(IAS)和冠状窦,最终沿尾颅方向到达左心房。IAB的存在与IAS厚度之间尚未确立关联。

目的

确定IAB程度与IAS厚度之间是否存在相关性,并确定IAS厚度是否可预测AF复发。

方法

纳入62例诊断为阵发性AF并接受导管消融的患者。IAB定义为P波时限≥120毫秒。通过心脏计算机断层扫描测量IAS厚度。

结果

在62例阵发性AF患者中,45例(72%)被诊断为IAB。24例(39%)被诊断为重度IAB。47例为男性。在平均49.8±22个月(范围12 - 60个月)的随访期内,32例(51%)出现AF复发。有IAB和无IAB的患者IAS厚度相似(4.5±2.0毫米对4.0±1.4毫米;p = 0.45),且不能预测AF。IAB患者的左心房大小显著增大(40.9±5.7毫米对37.2±4.0毫米;p = 0.03)。重度IAB可预测消融术后AF复发(比值比:3.34,可信区间:1.12 - 9.93;p = 0.03)。

结论

IAS厚度与IAB无显著相关性,不能预测AF复发。如先前所示,IAB是AF复发的独立预测指标。

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