Värendh M, Johannisson A, Hrubos-Strøm H, Andersson M
Department of Otorhinolaryngology, Skane University Hospital and Lund University, Sweden.
Occupational Therapy and Occupational Science, Lund University, Sweden.
Rhinology. 2017 Mar 1;55(1):45-52. doi: 10.4193/Rhin16.065.
Chronic Rhinosinusitis with Nasal Polyposis (CRSwNP) is a chronic disease that has a major impact on generic and disease-specific quality of life. Little is known about the influence of CRSwNP on sleep and what effect surgery for CRSwNP has on sleep quality. The aim of the study was to investigate sleep quality in patients with CRSwNP before and after endoscopic surgery.
Forty-two patients filled out four validated sleep questionnaires and one sino/nasal, disease specific quality of life questionnaire before surgery and three months later. A healthy control group filled out the same questionnaires at baseline and after three months.
An impact on sleep patterns was found in all sleep questionnaires and surgery clearly improved the quality of sleep. The Sino-nasal outcome test sum score decreased from median 51,5 to 26,5. Epworth sleepiness scale showed a decline in score from score 7.5 to 6.0. Surgery also reduced the risk for obstructive sleep apnoea in 13 patients evaluated by the Berlin Questionnaire and Multivariable Apnea Prediction Index.
Patients with CRSwNP had impaired sleep quality, daytime sleepiness, nasal patency, and risk for sleep apnea, all of which improved after corrective surgery.
伴鼻息肉的慢性鼻-鼻窦炎(CRSwNP)是一种对一般生活质量和疾病特异性生活质量有重大影响的慢性疾病。关于CRSwNP对睡眠的影响以及CRSwNP手术对睡眠质量有何影响,目前知之甚少。本研究的目的是调查内镜手术前后CRSwNP患者的睡眠质量。
42例患者在手术前和三个月后填写了四份经过验证的睡眠问卷和一份鼻窦/鼻腔疾病特异性生活质量问卷。一个健康对照组在基线时和三个月后填写了相同的问卷。
在所有睡眠问卷中均发现对睡眠模式有影响,手术明显改善了睡眠质量。鼻窦结局测试总分从中位数51.5降至26.5。爱泼沃斯思睡量表评分从7.5分降至6.0分。通过柏林问卷和多变量睡眠呼吸暂停预测指数评估,手术还降低了13例患者发生阻塞性睡眠呼吸暂停的风险。
CRSwNP患者的睡眠质量、日间嗜睡、鼻腔通畅度和睡眠呼吸暂停风险均受损,矫正手术后所有这些情况均有所改善。