Schmit J L, Tennenbaum F, Terminassian D, Westeel P F, Fournier A
Agressologie. 1989 May;30(5):269-72.
All different types of catheters can induce localized (subcutaneous) or systemic sepsis. Infection rates of 7 to 20% have been reported in the literature; catheter infection results from bacterial colonization of the skin, colonization of the line or may be secondary to blood born seeding. In a one year prospective study of 56 catheters in our unit, the rate of systemic infection was 5.3%, insertion site infection 3.6%, and contamination without infection 25%. No catheter with less than 10(2) colonies on a semi-quantitative culture method was infected. Prevention of catheter related sepsis needs strict aseptic protocols, and short duration of catheterization, antiseptic wrapping of the line; antimicrobial filtersets may further reduce the infection risk.
所有不同类型的导管都可引发局部(皮下)或全身性败血症。文献报道的感染率为7%至20%;导管感染源于皮肤细菌定植、导管定植,或可能继发于血行播散。在我们科室对56根导管进行的为期一年的前瞻性研究中,全身性感染率为5.3%,置管部位感染率为3.6%,无污染但有定植的情况为25%。采用半定量培养法时,菌落数少于10²的导管未发生感染。预防导管相关败血症需要严格的无菌操作规范、缩短置管时间、对导管进行抗菌包裹;抗菌滤器可能会进一步降低感染风险。