Pshenichnikova T Ia
Akush Ginekol (Mosk). 1989 Jul(7):42-5.
The paper presents the results of comprehensive studies of 100 infertile patients with oligomenorrhea. Familial predisposition to the impairments in the menstrual and reproductive functions was established as was a high rate of primary infertility and pregnancy wastage. Ninety per cent of the patients demonstrated ovarian dysfunction from the puberty, refractory anovulation was registered in the majority of the patients (70 per cent), intermittent in 22 and persistent ovulation only in 8 per cent of the examinees. Clinical and laboratory investigations confirmed hyperandrogenism in 80 per cent and hyperprolactinemia in 28 per cent of the patients. Laparoscopy demonstrated a high incidence of ovarian polycystosis (57 per cent), inflammatory genital changes (47 per cent), uterine myoma (7 per cent), and endometriosis of the external genitalia (7 per cent). There was no evidence of correlation between the content of plasma hormones, ovulatory disorders and endoscopic findings.
本文介绍了对100例月经过少的不孕患者进行综合研究的结果。研究确定了月经和生殖功能障碍存在家族易感性，以及原发性不孕和妊娠丢失的高发生率。90%的患者自青春期起出现卵巢功能障碍，大多数患者（70%）表现为难治性无排卵，22%为间歇性无排卵，仅8%的受检者持续排卵。临床和实验室检查证实，80%的患者存在高雄激素血症，28%的患者存在高催乳素血症。腹腔镜检查显示卵巢多囊症的发生率很高（57%）、生殖器炎症改变（47%）、子宫肌瘤（7%）和外阴子宫内膜异位症（7%）。没有证据表明血浆激素含量、排卵障碍和内镜检查结果之间存在相关性。
