Isoflurane inhibits enflurane metabolism in man.
作者信息
Oikkonen M P
机构信息
Department of Anaesthesia, Otolaryngological Hospital, Helsinki University Central Hospital, Finland.
出版信息
Anaesthesia. 1989 Sep;44(9):763-4. doi: 10.1111/j.1365-2044.1989.tb09265.x.
Abstract
Halogenated inhalation anaesthetics interfere with each other's hepatic microsomal metabolism. The increase in plasma inorganic fluoride concentration, caused by the metabolism of a standardised dose of enflurane, was attenuated by isoflurane given either before or after the enflurane exposure. It is concluded that isoflurane inhibits the metabolism of enflurane in man, a fact that might be advantageous in certain clinical situations.
摘要
Zotero 插件