Breger Tiffany L, Newman Jamie E, Mfangam Molu Brigitte, Akam Wilfred, Balimba Ashu, Atibu Joseph, Kiumbu Modeste, Azinyue Innocent, Hemingway-Foday Jennifer, Pence Brian W
a Department of Epidemiology , University of North Carolina at Chapel Hill , Chapel Hill , NC , USA.
b RTI International , Research Triangle Park , NC , USA.
AIDS Care. 2017 Jul;29(7):838-845. doi: 10.1080/09540121.2016.1271390. Epub 2016 Dec 26.
Poor retention in care is common among HIV-positive adults in sub-Saharan Africa settings and remains a key barrier to HIV management. We quantify the associations of disclosure of HIV status and referral to disclosure counseling with successful retention in care using data from three Cameroon clinics participating in the Phase 1 International epidemiologic Databases to Evaluate AIDS Central Africa cohort. Of 1646 patients newly initiating antiretroviral therapy between January 2008 and January 2011, 43% were retained in care following treatment initiation. Self-disclosure of HIV status to at least one person prior to treatment initiation was associated with a minimal increase in the likelihood of being retained in care (risk ratio [RR] = 1.14; 95% confidence interval (CI): 0.94, 1.38). However, referral to disclosure counseling was associated with a moderate increase in retention (RR = 1.37; 95% CI: 1.21, 1.55) and was not significantly modified by prior disclosure status (p = .3). Our results suggest that while self-disclosure may not significantly improve retention among patients receiving care at these Cameroon sites, counseling services may play an important role regardless of prior disclosure status.
在撒哈拉以南非洲地区,艾滋病毒呈阳性的成年人中护理留存率低的情况很常见,这仍然是艾滋病毒管理的一个关键障碍。我们利用喀麦隆三家参与第一阶段国际艾滋病流行病学数据库以评估艾滋病中非队列研究的诊所的数据,对艾滋病毒状况披露及转介至披露咨询与护理成功留存之间的关联进行了量化。在2008年1月至2011年1月期间开始接受抗逆转录病毒治疗的1646名患者中,43%在开始治疗后仍留在护理中。在开始治疗前向至少一人自我披露艾滋病毒状况与护理留存可能性的小幅增加相关(风险比[RR]=1.14;95%置信区间(CI):0.94,1.38)。然而,转介至披露咨询与留存率的适度增加相关(RR=1.37;95%CI:1.21,1.55),并且不受先前披露状况的显著影响(p=0.3)。我们的结果表明,虽然自我披露可能不会显著提高在这些喀麦隆地点接受护理的患者的留存率,但咨询服务可能发挥重要作用,无论先前的披露状况如何。