Faculty of Health Sciences, University of Buea, Buea, Cameroon.
Clinical Research Education Networking and Consultancy, Yaoundé, Cameroon.
Pan Afr Med J. 2021 Nov 2;40:129. doi: 10.11604/pamj.2021.40.129.22642. eCollection 2021.
retaining patients in antiretroviral treatment (ART) is essential for successful outcomes. Unfortunately, Cameroon continues to report suboptimal ART retention. This study focused on identifying determinants of ART retention in three HIV clinics in Cameroon within the HIV treat all context.
a medical chart review of 423 subjects who initiated ART between July and September 2016 in the Limbe, Bamenda and Jamot Hospitals. Patients' sociodemographic and clinical characteristics and ART retention data were abstracted using structured paper forms. Chi square test was used to assess bivariate associations. Logistic regression was used to adjust for confounders. P-value was set at <0.05 at 95% confidence interval.
the mean age was 40±11 years, and 65.1% were females. Antiretroviral treatment retention after 24 months was 309/392 (78.83%) and 30/423 (7.1%) were transferred-out, 11/423 (2.6%) reported dead and 73/423 (17.3%) lost to follow-up. HIV status disclosure (AOR 0.16 95% CI: 0.05-0.51, p<0.01) and age group 31-50 years (AOR 3.63, 95% CI: 1.04-12.59, P= 0.04) were associated with lower and higher ART retention respectively.
about a quarter of the participants were not retained in ART after 24 months. Patient-level factors determined ART retention. These factors should be considered in designing strategies to improve ART retention. More research is needed to identify other determinants of ART retention under the HIV treat all strategy.
将患者保留在抗逆转录病毒治疗(ART)中对于取得成功的结果至关重要。不幸的是,喀麦隆继续报告 ART 保留率不理想。本研究专注于在 HIV 治疗环境下,确定喀麦隆三个 HIV 诊所中接受 ART 的 423 名患者的 ART 保留决定因素。
对 2016 年 7 月至 9 月期间在 Limbe、Bamenda 和 Jamot 医院开始接受 ART 的 423 名患者的病历进行回顾。使用结构化纸质表格提取患者的社会人口学和临床特征以及 ART 保留数据。使用卡方检验评估二变量关联。使用逻辑回归调整混杂因素。置信区间为 95%,P 值<0.05。
平均年龄为 40±11 岁,65.1%为女性。24 个月后抗逆转录病毒治疗的保留率为 309/392(78.83%),30/423(7.1%)转出,11/423(2.6%)报告死亡,73/423(17.3%)失访。HIV 状态披露(AOR 0.16 95%CI:0.05-0.51,p<0.01)和 31-50 岁年龄组(AOR 3.63,95%CI:1.04-12.59,P=0.04)与较低和较高的 ART 保留率相关。
大约四分之一的参与者在 24 个月后没有保留在 ART 中。患者层面的因素决定了 ART 的保留率。在设计提高 ART 保留率的策略时,应考虑这些因素。需要进一步研究以确定在 HIV 治疗策略下 ART 保留的其他决定因素。