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驾驶行为终止与痴呆症的荟萃分析:性别因素重要吗?

Meta-analysis of Driving Cessation and Dementia: Does Sex Matter?

机构信息

Sunnybrook Research Institute, Toronto, Ontario, Canada.

Primary Care Research Unit, Toronto, Ontario, Canada.

出版信息

J Gerontol B Psychol Sci Soc Sci. 2018 Sep 20;73(7):1185-1189. doi: 10.1093/geronb/gbw158.

Abstract

OBJECTIVES

The number of drivers with dementia is expected to increase over the coming decades. Because dementia is associated with a higher risk of crashes, driving cessation becomes inevitable as the disease progresses, but many people with dementia resist stopping to drive. This meta-analysis examines whether there are sex differences in the prevalence and incidence of driving cessation among drivers with dementia and compares the pattern of sex differences in drivers with dementia to those without dementia.

METHOD

MEDLINE, PsycINFO, Scopus, and CINAHL were searched in July 2015 for observational studies of sex differences in driving cessation. Meta-analyses were performed using a random-effects model.

RESULTS

Twenty studies provided data on sex differences in driving cessation in older adults with or without dementia. Driving cessation was significantly more prevalent in women with dementia than men (odds ratio [OR] = 2.11, 95% confidence interval [CI] = 1.50-2.98), and the same pattern was found in women without dementia (OR = 2.74, 95% CI = 1.85-4.06).

DISCUSSION

Our findings suggest that the patterns of driving cessation differ between men and women with dementia, and this may have implications for sex-specific approaches designed to support drivers with dementia both before and after driving cessation.

摘要

目的

预计未来几十年痴呆症患者的数量将会增加。由于痴呆症与更高的事故风险相关,随着疾病的发展,停止驾驶是不可避免的,但许多痴呆症患者拒绝停止驾驶。本荟萃分析检查了痴呆症患者中停止驾驶的患病率和发生率是否存在性别差异,并比较了痴呆症患者与非痴呆症患者之间性别差异的模式。

方法

2015 年 7 月,我们在 MEDLINE、PsycINFO、Scopus 和 CINAHL 中搜索了关于痴呆症患者停止驾驶的性别差异的观察性研究。使用随机效应模型进行荟萃分析。

结果

20 项研究提供了关于有或没有痴呆症的老年人中停止驾驶的性别差异的数据。痴呆症女性停止驾驶的比例明显高于男性(优势比[OR] = 2.11,95%置信区间[CI] = 1.50-2.98),在没有痴呆症的女性中也存在同样的模式(OR = 2.74,95% CI = 1.85-4.06)。

讨论

我们的研究结果表明,痴呆症男性和女性的停止驾驶模式不同,这可能对旨在支持痴呆症患者在停止驾驶前后的特定性别方法具有重要意义。

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