Patraquim Cláudia, Gomes Maria Miguel, Garcez Carla, Leite Filipa, Oliva Tereza, Santos António, Pinto Armando
Pediatrics Department, Hospital de Braga, Sete Fontes, São Victor, 4710-243 Braga, Portugal.
Pediatrics Department, Portuguese Oncology Institute of Porto Francisco Gentil, 4200-072 Porto, Portugal.
Case Rep Pediatr. 2016;2016:8564389. doi: 10.1155/2016/8564389. Epub 2016 Nov 29.
Primary cutaneous lymphomas (PCL) are rare in pediatrics. Mycosis fungoides (MF) is the most frequent PCL diagnosed in childhood. There are various clinical variants of MF, including the hypopigmented MF (HMF). We present a 5-year-old boy with an 18-month history of progressive, generalized, nonpruritic hypopigmented lesions with central lacy erythema. He had no improvement with emollients. Skin biopsy showed typical features of HMF. He was treated with topical corticosteroids and tacrolimus and narrow-band ultraviolet B (NBUVB) phototherapy, with good response. HMF may mimic multiple skin disorders. Unusual hypopigmented skin lesions should be biopsied. Though phototherapy is effective, recurrence is common.
原发性皮肤淋巴瘤（PCL）在儿科中较为罕见。蕈样肉芽肿（MF）是儿童期最常见的原发性皮肤淋巴瘤。MF有多种临床变体，包括色素减退性MF（HMF）。我们报告一名5岁男孩，有18个月渐进性、全身性、非瘙痒性色素减退性皮损伴中央花边状红斑的病史。使用润肤剂治疗无效。皮肤活检显示HMF的典型特征。他接受了外用糖皮质激素、他克莫司和窄谱中波紫外线（NBUVB）光疗，反应良好。HMF可能会模仿多种皮肤疾病。不寻常的色素减退性皮肤病变应进行活检。虽然光疗有效，但复发很常见。
