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色素减退性蕈样肉芽肿:窄谱紫外线B诱导的临床、组织学及免疫组化缓解

Hypopigmented Mycosis Fungoides: Clinical, Histological, and Immunohistochemical Remission Induced by Narrow-band Ultraviolet B.

作者信息

Bisherwal Kavita, Singal Archana, Pandhi Deepika, Sharma Sonal

机构信息

Department of Dermatology and STD, University College of Medical Sciences and GTB Hospital, University of Delhi, New Delhi, India.

Department of Pathology, University College of Medical Sciences and GTB Hospital, University of Delhi, New Delhi, India.

出版信息

Indian J Dermatol. 2017 Mar-Apr;62(2):203-206. doi: 10.4103/ijd.IJD_365_16.

Abstract

Mycosis fungoides (MF) is the most common type of primary cutaneous lymphomas. Several clinical variants of MF have been described. Purely, hypopigmented variant of MF (HMF) is rare. Phototherapy, especially photochemotherapy (Psoralen and ultraviolet), is the most widely used method and is recommended as the first-line treatment for HMF. However, there are no standard guidelines for phototherapy as the disease is uncommon. We, hereby, report a 30-year-old woman with HMF in whom clinical, histopathological, and immunohistochemical remission was achieved following narrow-band ultraviolet B therapy.

摘要

蕈样肉芽肿(MF)是最常见的原发性皮肤淋巴瘤类型。MF已被描述有几种临床变体。单纯性色素减退型MF(HMF)较为罕见。光疗,尤其是光化学疗法(补骨脂素和紫外线),是应用最广泛的方法,被推荐作为HMF的一线治疗方法。然而,由于该疾病不常见,目前尚无光疗的标准指南。在此,我们报告一名30岁患有HMF的女性,在接受窄谱中波紫外线治疗后,实现了临床、组织病理学和免疫组化缓解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/22d6/5363147/6975a6c0561c/IJD-62-203-g001.jpg

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