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色素减退性蕈样肉芽肿:窄谱紫外线B诱导的临床、组织学及免疫组化缓解

Hypopigmented Mycosis Fungoides: Clinical, Histological, and Immunohistochemical Remission Induced by Narrow-band Ultraviolet B.

作者信息

Bisherwal Kavita, Singal Archana, Pandhi Deepika, Sharma Sonal

机构信息

Department of Dermatology and STD, University College of Medical Sciences and GTB Hospital, University of Delhi, New Delhi, India.

Department of Pathology, University College of Medical Sciences and GTB Hospital, University of Delhi, New Delhi, India.

出版信息

Indian J Dermatol. 2017 Mar-Apr;62(2):203-206. doi: 10.4103/ijd.IJD_365_16.

DOI:10.4103/ijd.IJD_365_16
PMID:28400643
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5363147/
Abstract

Mycosis fungoides (MF) is the most common type of primary cutaneous lymphomas. Several clinical variants of MF have been described. Purely, hypopigmented variant of MF (HMF) is rare. Phototherapy, especially photochemotherapy (Psoralen and ultraviolet), is the most widely used method and is recommended as the first-line treatment for HMF. However, there are no standard guidelines for phototherapy as the disease is uncommon. We, hereby, report a 30-year-old woman with HMF in whom clinical, histopathological, and immunohistochemical remission was achieved following narrow-band ultraviolet B therapy.

摘要

蕈样肉芽肿(MF)是最常见的原发性皮肤淋巴瘤类型。MF已被描述有几种临床变体。单纯性色素减退型MF(HMF)较为罕见。光疗,尤其是光化学疗法(补骨脂素和紫外线),是应用最广泛的方法,被推荐作为HMF的一线治疗方法。然而,由于该疾病不常见,目前尚无光疗的标准指南。在此,我们报告一名30岁患有HMF的女性,在接受窄谱中波紫外线治疗后,实现了临床、组织病理学和免疫组化缓解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/22d6/5363147/b239c2669b75/IJD-62-203-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/22d6/5363147/6975a6c0561c/IJD-62-203-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/22d6/5363147/987a561d1237/IJD-62-203-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/22d6/5363147/9b59e1e334cb/IJD-62-203-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/22d6/5363147/c83d320774cb/IJD-62-203-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/22d6/5363147/b239c2669b75/IJD-62-203-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/22d6/5363147/6975a6c0561c/IJD-62-203-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/22d6/5363147/987a561d1237/IJD-62-203-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/22d6/5363147/9b59e1e334cb/IJD-62-203-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/22d6/5363147/c83d320774cb/IJD-62-203-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/22d6/5363147/b239c2669b75/IJD-62-203-g005.jpg

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2
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3
Mycosis fungoides in Iranian population: an epidemiological and clinicopathological study.伊朗人群中的蕈样肉芽肿:一项流行病学和临床病理学研究。
Dermatol Res Pract. 2023 Jan 31;2023:1360740. doi: 10.1155/2023/1360740. eCollection 2023.
4
Hypopigmented patches in an 8-year-old boy.一名8岁男孩身上的色素减退斑。
Malays Fam Physician. 2018 Apr 30;13(1):49-51. eCollection 2018.
J Skin Cancer. 2015;2015:306543. doi: 10.1155/2015/306543. Epub 2015 Jan 28.
4
Hypopigmented mycosis fungoides: a review of its clinical features and pathophysiology.色素减退性蕈样肉芽肿:临床特征与病理生理学综述
An Bras Dermatol. 2013 Nov-Dec;88(6):954-60. doi: 10.1590/abd1806-4841.20132336.
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Hypopigmented mycosis fungoides in a chinese woman.一名中国女性的色素减退性蕈样肉芽肿
Indian J Dermatol. 2013 Mar;58(2):161. doi: 10.4103/0019-5154.108093.
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Phototherapy for hypopigmented mycosis fungoides in Asians.亚洲人蕈样肉芽肿病色素减退的光疗。
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