Bosi G, Giari L, DePasquale J A, Carosi A, Lorenzoni M, Dezfuli B Sayyaf
Department of Veterinary Sciences and Technologies for Food Safety, Università degli Studi di Milano, Milan, Italy.
Department of Life Sciences & Biotechnology, University of Ferrara, Ferrara, Italy.
J Fish Dis. 2017 Aug;40(8):1001-1014. doi: 10.1111/jfd.12576. Epub 2016 Dec 27.
Histopathological, immunofluorescence and ultrastructural studies were conducted on the intestines of four fish species infected with different taxa of enteric helminths. Brown trout (Salmo trutta trutta), eel (Anguilla anguilla) and tench (Tinca tinca) obtained from Lake Piediluco (central Italy) were examined. Brown trout and eel were infected with two species of acanthocephalans, and tench was parasitized with a tapeworm species. In addition to the above site, specimens of chub (Squalius cephalus) and brown trout infected with an acanthocephalan were examined from the River Brenta (north Italy). Moreover, eels were examined from a brackish water, Comacchio lagoons (north Italy), where one digenean species was the predominant enteric worm. All the helminths species induced a similar response, the hyperplasia of the intestinal mucous cells, particularly of those secreting acid mucins. Local endocrine signals seemed to affect the production and secretion of mucus in the parasitized fish, as worms often were surrounded by an adherent mucus layer or blanket. This is the first quantitative report of enteric worm effects on the density of various mucous cell types and on the mucus composition in intestine of infected/uninfected conspecifics. We provide a global comparison between the several fish-helminth systems examined.
对感染了不同种类肠道蠕虫的四种鱼类的肠道进行了组织病理学、免疫荧光和超微结构研究。对从意大利中部的皮耶迪卢科湖采集的褐鳟（Salmo trutta trutta）、鳗鱼（Anguilla anguilla）和丁鱥（Tinca tinca）进行了检查。褐鳟和鳗鱼感染了两种棘头虫，丁鱥感染了一种绦虫。除上述地点外，还对来自意大利北部布伦塔河的感染了棘头虫的雅罗鱼（Squalius cephalus）和褐鳟标本进行了检查。此外，还对来自意大利北部科马基奥咸水湖的鳗鱼进行了检查，在那里一种复殖吸虫是主要的肠道蠕虫。所有的蠕虫种类都引发了类似的反应，即肠道黏液细胞增生，尤其是分泌酸性黏液的细胞。局部内分泌信号似乎影响了寄生鱼类中黏液的产生和分泌，因为蠕虫周围常常有一层附着的黏液层或黏液毯。这是关于肠道蠕虫对感染/未感染同种鱼类肠道中各种黏液细胞类型密度和黏液成分影响的第一份定量报告。我们对所研究的几种鱼类 - 蠕虫系统进行了全面比较。
