Middeke M
Medizinische Poliklinik der Universität München.
Arch Gynecol Obstet. 1989;245(1-4):244-7. doi: 10.1007/BF02417260.
During the last 10 years, radioligand binding studies have greatly advanced our knowledge about adrenoceptors in circulating lymphocytes. In essential hypertension the activity of the sympathetic system seems to be altered. Stimulation of the sympathetic system leads to rapid increase of lymphocyte beta-2-adrenoceptor density. In contrast, gestational hypertension is characterized by a decrease in cardiac output and enhanced arteriolar and venolar resistance. Peripheral resistance is modulated by alpha- and beta adrenoceptors and further studies are needed to characterize and quantify adrenoceptor density in gestational hypertension.
在过去十年中，放射性配体结合研究极大地增进了我们对循环淋巴细胞中肾上腺素能受体的了解。在原发性高血压中，交感神经系统的活性似乎发生了改变。刺激交感神经系统会导致淋巴细胞β-2-肾上腺素能受体密度迅速增加。相比之下，妊娠高血压的特征是心输出量减少以及小动脉和小静脉阻力增加。外周阻力受α和β肾上腺素能受体调节，需要进一步研究来确定和量化妊娠高血压中肾上腺素能受体的密度。
