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本文引用的文献

1
Comparative study of whole genome amplification and next generation sequencing performance of single cancer cells.单个癌细胞的全基因组扩增与下一代测序性能的比较研究。
Oncotarget. 2016 Jul 19;8(34):56066-56080. doi: 10.18632/oncotarget.10701. eCollection 2017 Aug 22.
2
Accession of Tumor Heterogeneity by Multiplex Transcriptome Profiling of Single Circulating Tumor Cells.通过对单个循环肿瘤细胞进行多重转录组谱分析来获得肿瘤异质性。
Clin Chem. 2016 Nov;62(11):1504-1515. doi: 10.1373/clinchem.2016.260299. Epub 2016 Sep 14.
3
HER2 expression identifies dynamic functional states within circulating breast cancer cells.HER2表达可识别循环乳腺癌细胞内的动态功能状态。
Nature. 2016 Sep 1;537(7618):102-106. doi: 10.1038/nature19328. Epub 2016 Aug 24.
4
Circulating tumor DNA analysis detects minimal residual disease and predicts recurrence in patients with stage II colon cancer.循环肿瘤DNA分析可检测II期结肠癌患者的微小残留病并预测复发。
Sci Transl Med. 2016 Jul 6;8(346):346ra92. doi: 10.1126/scitranslmed.aaf6219.
5
Identification of Circulating Tumor DNA for the Early Detection of Small-cell Lung Cancer.循环肿瘤DNA的鉴定用于小细胞肺癌的早期检测
EBioMedicine. 2016 Aug;10:117-23. doi: 10.1016/j.ebiom.2016.06.032. Epub 2016 Jun 25.
6
Ultra-deep sequencing detects ovarian cancer cells in peritoneal fluid and reveals somatic TP53 mutations in noncancerous tissues.超深度测序可检测腹水中的卵巢癌细胞，并揭示非癌组织中的体细胞TP53突变。
Proc Natl Acad Sci U S A. 2016 May 24;113(21):6005-10. doi: 10.1073/pnas.1601311113. Epub 2016 May 5.
7
The Conundrum of Genetic "Drivers" in Benign Conditions.良性疾病中基因“驱动因素”的难题
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Integrated digital error suppression for improved detection of circulating tumor DNA.用于改善循环肿瘤DNA检测的集成数字误差抑制
Nat Biotechnol. 2016 May;34(5):547-555. doi: 10.1038/nbt.3520. Epub 2016 Mar 28.
9
Clinical Applications of Circulating Tumor Cells and Circulating Tumor DNA as Liquid Biopsy.循环肿瘤细胞和循环肿瘤 DNA 作为液体活检的临床应用。
Cancer Discov. 2016 May;6(5):479-91. doi: 10.1158/2159-8290.CD-15-1483. Epub 2016 Mar 11.
10
RNA-Seq of Tumor-Educated Platelets Enables Blood-Based Pan-Cancer, Multiclass, and Molecular Pathway Cancer Diagnostics.肿瘤衍生血小板的RNA测序实现基于血液的泛癌、多类别和分子通路癌症诊断。
Cancer Cell. 2015 Nov 9;28(5):666-676. doi: 10.1016/j.ccell.2015.09.018. Epub 2015 Oct 29.

基于血液的循环游离DNA和肿瘤细胞分析用于早期癌症检测

Blood-Based Analysis of Circulating Cell-Free DNA and Tumor Cells for Early Cancer Detection.

作者信息

Pantel Klaus

机构信息

Institute of Tumor Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

出版信息

PLoS Med. 2016 Dec 27;13(12):e1002205. doi: 10.1371/journal.pmed.1002205. eCollection 2016 Dec.

DOI:10.1371/journal.pmed.1002205
PMID:28027295
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5189941/
Abstract

In a Perspective, Klaus Pantel discusses prospects for use of cell-free DNA and circulating tumor cells in cancer detection.

摘要

克劳斯·潘特尔在一篇《观点》文章中讨论了游离DNA和循环肿瘤细胞在癌症检测中的应用前景。