影像学工具在卵巢交界性肿瘤诊断中的作用：一项系统评价与Meta分析
Role of Imaging Tools for the Diagnosis of Borderline Ovarian Tumors: A Systematic Review and Meta-Analysis.
作者信息
Borrelli Giuliano Moysés, de Mattos Leandro Accardo, Andres Marina de Paula, Gonçalves Manoel Orlando, Kho Rosanne M, Abrão Mauricio Simões
机构信息
Department of Obstetrics and Gynecology, Hospital das Clínicas, Medical School, University of São Paulo, São Paulo, Brazil.
Department of Obstetrics and Gynecology, Cleveland Clinic, Cleveland, Ohio.
出版信息
J Minim Invasive Gynecol. 2017 Mar-Apr;24(3):353-363. doi: 10.1016/j.jmig.2016.12.012. Epub 2016 Dec 24.
Borderline ovarian tumors (BOTs) have a low malignant potential and occur most often in young women. Its preoperative diagnosis can improve surgical strategy and reproductive approach. This study systematically reviews the literature for the accuracy of transvaginal ultrasound (TVUS), magnetic resonance (MRI), and computed tomography (CT) in the diagnostic of BOTs. We conducted a search in PubMed/Medline of articles in English from the last 5 years and included 14 studies for systematic review, 9 of them in the meta-analysis. The pooled sensibility and specificity was respectively 77.0% and 83.0% for TVUS (5 studies) and 85% and 74% for MRI (4 studies) in differentiating benign from malignant BOTs. CT and positron emission tomography (PET)-CT techniques were heterogeneous between studies, so a meta-analysis was not performed for the 4 studies on CT and PET-CT. However, these 4 studies have also shown a high accuracy in differentiating BOTs from malignant ovarian cancers.
卵巢交界性肿瘤（BOTs）恶性潜能低，最常发生于年轻女性。其术前诊断可改善手术策略和生殖方式。本研究系统回顾了经阴道超声（TVUS）、磁共振成像（MRI）和计算机断层扫描（CT）诊断BOTs的准确性的相关文献。我们在PubMed/Medline中检索了过去5年的英文文章，纳入14项研究进行系统评价，其中9项纳入荟萃分析。在鉴别BOTs的良恶性方面，TVUS（5项研究）的合并敏感性和特异性分别为77.0%和83.0%，MRI（4项研究）分别为85%和74%。CT和正电子发射断层扫描（PET）-CT技术在各研究之间存在异质性，因此未对4项关于CT和PET-CT的研究进行荟萃分析。然而，这4项研究也显示出在鉴别BOTs与恶性卵巢癌方面具有较高的准确性。
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