Pitt H A, Kaufman S L, Coleman J, White R I, Cameron J L
Department of Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland.
Ann Surg. 1989 Oct;210(4):417-25; discussion 426-7. doi: 10.1097/00000658-198910000-00001.
At The Johns Hopkins Hospital from 1979 through 1987, 42 patients had 45 procedures for benign postoperative biliary strictures. Three patients were managed with both surgery and balloon dilatation. Twenty-five patients underwent surgical repair with Roux-Y choledocho- or hepaticojejunostomy with postoperative transhepatic stenting for a mean of 13.8 +/- 1.3 months. Twenty patients had balloon dilatation a mean of 3.9 times and were stented transhepatically for a mean of 13.3 +/- 2.0 months. The two groups were similar with respect to multiple parameters that might have influenced outcome. Mean length of follow-up was 57 +/- 7 and 59 +/- 6 months for surgery and balloon dilatation, respectively. No patients died after any of the procedures. The same definition of a successful outcome was applied to both groups and was achieved in 88% of the surgical and in only 55% of the balloon dilatation patients (p less than 0.02). Significant hemobilia occurred more often with balloon dilatation (20% vs. 4%, p less than 0.02). The total hospital stay and cost of balloon dilatation was not significantly different from surgery. We conclude that surgical repair of benign postoperative strictures results in fewer problems that require further therapy. Nevertheless balloon dilatation is an alternative for patients who are at high risk or who are unwilling to undergo another operation.
1979年至1987年期间,在约翰霍普金斯医院,42例患者因良性术后胆管狭窄接受了45次手术。3例患者同时接受了手术和球囊扩张治疗。25例患者接受了Roux-Y胆管空肠吻合术或肝空肠吻合术的手术修复,并在术后经肝置入支架,平均时间为13.8±1.3个月。20例患者平均接受了3.9次球囊扩张,并经肝置入支架,平均时间为13.3±2.0个月。两组在可能影响治疗结果的多个参数方面相似。手术组和球囊扩张组的平均随访时间分别为57±7个月和59±6个月。所有手术均无患者死亡。两组对成功治疗结果的定义相同,手术组88%的患者达到了该定义,而球囊扩张组只有55%的患者达到该定义(p<0.02)。球囊扩张术后严重胆道出血的发生率更高(20%对4%,p<0.02)。球囊扩张术的总住院时间和费用与手术相比无显著差异。我们得出结论,良性术后狭窄的手术修复导致需要进一步治疗的问题较少。然而,对于高危患者或不愿接受再次手术的患者,球囊扩张术是一种替代选择。