Donà S, Bacchi E, Moghetti P
Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and AOUI of Verona, P.le Stefani, 1, 37126, Verona, Italy.
J Endocrinol Invest. 2017 May;40(5):463-469. doi: 10.1007/s40618-016-0599-1. Epub 2016 Dec 27.
Polycystic ovary syndrome (PCOS) is a common and heterogeneous endocrine disorder, affecting 8-12% of reproductive-aged women. Insulin resistance and body fat excess are common features in these subjects. Increased physical activity and diet modifications are the first recommended approach in the management of these women, at least in overweight/obese subjects. Evaluation of cardiorespiratory fitness (CRF) is important in assessing exercise performance and in monitoring the effects of physical exercise interventions. Several studies have shown that CRF may be impaired in metabolic and endocrine disorders. However, there are little data on this issue in PCOS women. The aim of this narrative review is to critically evaluate whether aerobic capacity is altered in PCOS women, focusing on maximal oxygen uptake.
An updated search of the literature was performed, identifying papers with maximal oxygen consumption measurements in women with PCOS compared to healthy controls.
We have identified six studies on this specific topic: four of them showed an alteration of maximal oxygen consumption in PCOS women, whereas two did not. However, taken together these studies suggest that CRF may be strikingly impaired in both normal-weight and overweight/obese subjects with this condition.
Women with PCOS appear to be characterized by a reduced cardiopulmonary fitness. However, further research on this topic is needed. This information may hopefully help clinicians and exercise specialist in planning individualized exercise programs aimed at improving the metabolic and endocrine outcomes in these women.
多囊卵巢综合征（PCOS）是一种常见的异质性内分泌疾病，影响8% - 12%的育龄妇女。胰岛素抵抗和体脂过多是这些患者的常见特征。增加体育活动和调整饮食是管理这些女性的首选方法，至少对于超重/肥胖患者是如此。评估心肺适能（CRF）对于评估运动表现和监测体育锻炼干预的效果很重要。多项研究表明，CRF可能在代谢和内分泌疾病中受损。然而，关于PCOS女性这一问题的数据很少。本叙述性综述的目的是批判性地评估PCOS女性的有氧能力是否改变，重点关注最大摄氧量。
对文献进行了更新检索，确定了与健康对照相比，测量PCOS女性最大耗氧量的论文。
我们确定了六项关于这一特定主题的研究：其中四项显示PCOS女性的最大耗氧量有改变，而两项没有。然而，综合这些研究表明，在患有这种疾病的正常体重和超重/肥胖受试者中，CRF可能均显著受损。
PCOS女性似乎具有心肺适能降低的特征。然而，需要对这一主题进行进一步研究。这些信息有望帮助临床医生和运动专家制定个性化的运动计划，以改善这些女性的代谢和内分泌状况。
