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一种针对特定国家的汉赛巴尔通体抗原在IgM间接荧光抗体检测中用于改善猫抓病诊断的效用。

The utility of a country-specific Bartonella henselae antigen in an IgM-indirect fluorescent antibody assay for the improved diagnosis of cat scratch disease.

作者信息

Tsuneoka Hidehiro, Yanagihara Masashi, Tanimoto Ayano, Tokuda Nobuko, Otsuyama Ken-Ichiro, Nojima Junzo, Ichihara Kiyoshi

机构信息

Department of Clinical Laboratory Science, Graduate School of Medicine, Yamaguchi University, Ube, Yamaguchi 755-8505, Japan.

Department of Clinical Laboratory Science, Graduate School of Medicine, Yamaguchi University, Ube, Yamaguchi 755-8505, Japan.

出版信息

Diagn Microbiol Infect Dis. 2017 Jan;87(1):22-24. doi: 10.1016/j.diagmicrobio.2016.10.015. Epub 2016 Oct 11.

DOI:10.1016/j.diagmicrobio.2016.10.015
PMID:28029424
Abstract

Bartonella henselae strains genetically differ among nations. The utility of Japanese-specific YH-01 strain was investigated in developing indirect fluorescence antibody assay (IFA) for IgM in comparison with conventional IFA employing Houston-1 strain by testing 100 Japanese patients suspected of cat scratch disease. The country-specific IFA greatly improved the accuracy of diagnosis.

摘要

汉赛巴尔通体菌株在不同国家存在基因差异。通过检测100名疑似猫抓病的日本患者，研究了日本特有的YH - 01菌株在开发IgM间接荧光抗体试验（IFA）中的效用，并与采用休斯顿-1菌株的传统IFA进行了比较。这种针对特定国家的IFA极大地提高了诊断准确性。

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