Colby T V, Bilbao J E, Battifora H, Unni K K
Department of Laboratory Medicine, Mayo Clinic, Rochester, Minn.
Arch Pathol Lab Med. 1989 Oct;113(10):1147-50.
Five neoplasms were initially believed to represent primary osteosarcomas of the lung. Of the five cases, two were reinterpreted as carcino-sarcomas based on the identification of epithelial elements on further histologic sectioning and immunohistologic study in one and on immunohistologic study alone in the second. The differential diagnosis of carcinosarcoma should be considered for any lesion believed to represent a primary sarcoma of the lung, and in some cases carcinomatous elements may only be demonstrable by immunohistologic means.
最初认为有五种肿瘤代表肺原发性骨肉瘤。在这五个病例中，其中一例经进一步组织切片和免疫组织学研究发现上皮成分，另一例仅经免疫组织学研究，这两例被重新诊断为癌肉瘤。对于任何被认为是肺原发性肉瘤的病变都应考虑癌肉瘤的鉴别诊断，在某些情况下，癌性成分可能仅通过免疫组织学方法才能显示出来。
