Dales Robert E, Cakmak Sabit
Population Studies Division, Health Canada, Ottawa, Ontario, Canada.
School of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
PLoS One. 2016 Dec 28;11(12):e0168931. doi: 10.1371/journal.pone.0168931. eCollection 2016.
Both air pollution exposure and the presence of mental illness are associated with an increased risk of physical illness.
To determine whether or not children with less favourable mental health are more susceptible to pulmonary and cardiovascular effects of ambient air pollution, compared to those who are mentally healthy.
We carried out a cross-sectional study of 1,883 children between the ages of 6 and 17 years of age who participated in the Canadian Health Measures population survey between 2007 and 2009. Subjects were assigned the air pollution values obtained from the National Air Pollution monitor closest to their neighborhood. Lung function, heart rate and blood pressure were stratified by indicators of mental health. The latter were ascertained by questions about feelings of happiness, a diagnosed mood disorder, and the emotional symptom subscale of the Strengths and Difficulties Questionnaire.
Among those who reported a mood disorder, an interquartile increase in ozone was associated with increases in systolic and diastolic pressures of 3.8 mmHg (95% CI 1.6, 5.9) and 3.0mmHg (95%CI 0.9, 5.2) respectively, and a decreases in FVC of 7.6% (95% CI 2.9, 12.3). No significant changes in these variables were observed in those who did not report a mood disorder. Among those with unfavourable emotional symptoms, ozone was associated with a 6.4% (95% CI 1.7, 11.3) increase in heart rate, a 4.1% (95%CI 1.2, 7.1) increase in systolic blood pressure, and a 6.0% (95% CI 1.4, 10.6) decrease in FEVl. No significant effect was seen in these variables among those with no emotional symptoms.
In the Canadian population, children who report mood disorders or unfavourable emotional symptoms appear to be more vulnerable to the adverse physiologic effects of air pollution.
暴露于空气污染以及患有精神疾病均与身体疾病风险增加相关。
确定心理健康状况较差的儿童与心理健康的儿童相比，是否更容易受到环境空气污染对肺部和心血管系统的影响。
我们对1883名6至17岁的儿童进行了一项横断面研究，这些儿童参与了2007年至2009年的加拿大健康测量人口调查。受试者被赋予从最靠近其社区的国家空气污染监测站获得的空气污染值。肺功能、心率和血压按心理健康指标进行分层。心理健康指标通过关于幸福感的问题、确诊的情绪障碍以及优势与困难问卷的情绪症状子量表来确定。
在报告患有情绪障碍的儿童中，臭氧四分位间距增加分别与收缩压升高3.8 mmHg（95%可信区间1.6, 5.9）和舒张压升高3.0 mmHg（95%可信区间0.9, 5.2）相关，以及用力肺活量降低7.6%（95%可信区间2.9, 12.3）。在未报告情绪障碍的儿童中，这些变量未观察到显著变化。在情绪症状不良的儿童中，臭氧与心率增加6.4%（95%可信区间1.7, 11.3）、收缩压升高4.1%（95%可信区间1.2, 7.1）以及第一秒用力呼气容积降低6.0%（95%可信区间1.4, 10.6）相关。在无情绪症状的儿童中，这些变量未观察到显著影响。
在加拿大人群中，报告患有情绪障碍或情绪症状不良的儿童似乎更容易受到空气污染的不良生理影响。
