Wilson M C, Shields M B
Department of Ophthalmology, Duke University Eye Center, Durham, NC 27710.
Arch Ophthalmol. 1989 Oct;107(10):1465-8. doi: 10.1001/archopht.1989.01070020539035.
Iridocorneal endothelial syndrome is generally considered to have three major variations: Chandler's syndrome, progressive (essential) iris atrophy, and the Cogan-Reese syndrome. To better understand the clinical significance of this classification, we studied the medical records of 37 consecutive patients from our practice, comparing the presentation and course of the three subgroups. Chandler's syndrome was the most common clinical variant within this spectrum of disease (21 cases). Patients with Chandler's syndrome had more severe corneal edema than the rest of the group, while those with progressive iris atrophy (8 cases) or the Cogan-Reese syndrome (8 cases) had worse secondary glaucoma.
钱德勒综合征、进行性（原发性）虹膜萎缩和科根-里斯综合征。为了更好地理解这种分类的临床意义，我们研究了我们诊所连续37例患者的病历，比较了三个亚组的临床表现和病程。钱德勒综合征是该疾病谱中最常见的临床变体（21例）。钱德勒综合征患者的角膜水肿比该组其他患者更严重，而进行性虹膜萎缩患者（8例）或科根-里斯综合征患者（8例）的继发性青光眼更严重。
