Suliga Edyta, Kozieł Dorota, Głuszek Stanisław
Faculty of Medicine and Health Sciences, Jan Kochanowski University, Kielce, Poland.
Ann Agric Environ Med. 2016 Dec 23;23(4):631-635. doi: 10.5604/12321966.1226858.
The prevalence of metabolic syndrome and overweight in individuals with normal body weight is connected with higher exposure to type 2 diabetes and cardiovascular diseases. The aim of the study was to evaluate the risk and frequency of occurrence of metabolic syndrome and each of its components among individuals with normal weight.
Data were obtained by structured interview, and by measurements of anthropometric factors and blood analyses among 13,172 individuals aged 37-66. The risk of occurrence of metabolic syndrome was analysed in tertiles within the normal range of BMI (18.5-24.9 kg/m ).
Metabolic syndrome was diagnosed in 17.27% of individuals with normal weight. A significant increase in the risk of occurrence of metabolic syndrome in females was observed within the second (OR = 2.22; 95% CI: 1.63-3.05) and the third (OR = 3.97; 95% CI: 2.97-5.36) tertiles of normal BMI values. In males, a significantly higher risk of occurrence of metabolic syndrome was noted only in the highest BMI tertile (OR = 2.16; 95% CI: 1.26-3.83), compared to the reference level.
A high frequency of occurrence of metabolic syndrome risk factors was observed among individuals with BMI close to the upper cut-off point of the normal range. In order to early diagnose metabolically obese individuals with normal weight it is necessary to check the waist circumference when BMI ≥ 22.5 kg/m in females, and BMI ≥ 23.8 kg/m in males, where abnormal values should be a signal that further examinations should be performed to determine other risk factors of metabolic syndrome.
正常体重个体中代谢综合征和超重的患病率与2型糖尿病和心血管疾病的更高暴露相关。本研究的目的是评估正常体重个体中代谢综合征及其各组分的发生风险和频率。
通过结构化访谈、人体测量因素测量和血液分析，获取了13172名年龄在37 - 66岁个体的数据。在BMI正常范围（18.5 - 24.9 kg/m²）内按三分位数分析代谢综合征的发生风险。
在正常体重个体中，17.27%被诊断为代谢综合征。在正常BMI值的第二个三分位数（OR = 2.22；95% CI：1.63 - 3.05）和第三个三分位数（OR = 3.97；95% CI：2.97 - 5.36）中，女性代谢综合征发生风险显著增加。在男性中，仅在最高BMI三分位数中观察到代谢综合征发生风险显著高于参考水平（OR = 2.16；95% CI：1.26 - 3.83）。
在BMI接近正常范围上限的个体中，观察到代谢综合征危险因素的高发生率。为了早期诊断体重正常的代谢性肥胖个体，当女性BMI≥22.5 kg/m²，男性BMI≥23.8 kg/m²时，有必要检查腰围，异常值应作为进一步检查以确定代谢综合征其他危险因素的信号。
