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伏立康唑诱发的亚急性皮肤型红斑狼疮一例,患者为一名患有曲霉病的成年人。

Voriconazole-Induced Subacute Cutaneous Lupus Erythematosus in an Adult With Aspergillosis.

作者信息

Ezra Navid, Jourabchi Natanel, Mousdicas Nico

机构信息

Department of Dermatology, Indiana University School of Medicine, Indianapolis, IN;

Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD.

出版信息

Skinmed. 2016 Dec 1;14(6):461-463. eCollection 2016.

PMID:28031137
Abstract

A 59-year-old man was treated with voriconazole for chronic invasive aspergillosis and who subsequently developed subacute cutaneous lupus erythematosus (SCLE). The patient presented with a 6-week history of multiple erythematous papulosquamous lesions on his chest, upper and lower extremities, and back (Figure 1). They were nonpruritic and nonpainful. He was afebrile and otherwise well. He had no history of extensive sun exposure prior to the appearance of the eruption. He had been taking voriconazole for about 3 months prior to the onset of lesions. He denied any family history of connective tissue disease.

摘要

一名59岁男性因慢性侵袭性曲霉病接受伏立康唑治疗,随后出现亚急性皮肤型红斑狼疮(SCLE)。患者胸部、上下肢及背部出现多发红斑丘疹鳞屑性皮损,病史6周(图1)。皮损无瘙痒及疼痛。患者无发热,其他情况良好。皮疹出现前无长时间日晒史。皮损出现前约3个月一直在服用伏立康唑。患者否认结缔组织病家族史。

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